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Proteintech
CPEB1 Polyclonal Antibody
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Product Details
13274-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Echinoderm,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CPEB1 Fusion Protein Ag3994 (188-486 aa encoded by BC035348)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Amount
34.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody may recognize several bands, but only ~56 kDa band is the right one, other (40~50 kDa) is un-specific bands.
Immunogen sequence: WDLLEAPKD PFSIEREARL HRQAAAVNEA TCTWSGQLPP RNYKNPIYSC KVFLGGVPWD ITEAGLVNTF RVFGSLSVEW PGKDGKHPRC PPKGYVYLVF ELEKSVRSLL QACSHDPLSP DGLSEYYFKM SSRRMRCKEV QVIPWVLADS NFVRSPSQRL DPSRTVFVGA LHGMLNAEAL AAILNDLFGG VVYAGIDTDK HKYPIGSGRV TFNNQRSYLK AVSAAFVEIK TTKFTKKVQI DPYLEDSLCH ICSSQPGPFF CRDQVCFKYF CRSCWHWRHS MEGLRHHSPL MRNQKNRDSS (188-486 aa encoded by BC035348)
Target Information
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the nuclear membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the nuclear membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CEBP; CPE-binding protein 1; CPE-BP1; CPEB; CPEB-1; Cytoplasmic polyadenylation element-binding protein 1; FLJ13203; h-CEBP; mCPEB-1; MGC34136; MGC60106; RNA binding protein; unnamed protein product
Gene Aliases: AU024112; CPE-BP1; CPEB; CPEB-1; CPEB1; h-CPEB; hCPEB-1; mCPEB
UniProt ID: (Human) Q9BZB8, (Mouse) P70166, (Rat) P0C279
Entrez Gene ID: (Human) 64506, (Mouse) 12877, (Rat) 293056
translation repressor activity, nucleic acid binding
nucleic acid binding
RNA binding
mRNA 3'-UTR binding
protein binding
translation factor activity, RNA binding
mRNA 3'-UTR AU-rich region binding
ribosome binding
translation regulator activity
metal ion binding
nucleotide binding
mRNA binding
mRNA polyadenylation factor
mRNA processing
translation
regulation of translation
negative regulation of translation
regulation of mRNA 3'-end processing
cellular response to insulin stimulus
cellular response to amino acid stimulus
cellular response to hypoxia
negative regulation of cytoplasmic translation
synaptonemal complex assembly
negative regulation of cell proliferation
positive regulation of neuron projection development
positive regulation of cell migration
positive regulation of translation
regulation of neuronal synaptic plasticity
mRNA transport
positive regulation of nitric-oxide synthase biosynthetic process
cellular response to lipopolysaccharide
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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