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Proteintech
CPLX2 Polyclonal Antibody
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Product Details
18149-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CPLX2 Fusion Protein Ag12838 (1-134 aa encoded by BC093706)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDFVMKQAL GGATKDMGKM LGGEEEKDPD AQKKEEERQE ALRQQEEERK AKHARMEAER EKVRQQIRDK YGLKKKEEKE AEEKAALEQP CEGSLTRPKK AIPAGCGDEE EEEEESILDT VLKYLPGPLQ DMFKK (1-134 aa encoded by BC093706)
Target Information
Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 921-L; Complexin II; Complexin-2; CPX II; CPX-II; DKFZp547D155; member of the SNARE family of proteins; MGC138492; synaphin 1; Synaphin-1; unnamed protein product
Gene Aliases: 921-L; AI413745; AW492120; CPLX2; CPX-2; CPX2; Hfb1
UniProt ID: (Human) Q6PUV4, (Rat) P84087, (Mouse) P84086
Entrez Gene ID: (Human) 10814, (Rat) 116657, (Mouse) 12890
neurotransmitter transport
exocytosis
vesicle docking involved in exocytosis
nervous system development
synaptic vesicle exocytosis
regulation of exocytosis
cell differentiation
regulation of synaptic vesicle fusion to presynaptic membrane
positive regulation of synaptic plasticity
mast cell degranulation
modulation of synaptic transmission
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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