Immunogen sequence: RNQRIVQLI QDTRIHILPS MNPDGYEVAA AQGPNKPGYL VGRNNANGVD LNRNFPDLNT YIYYNEKYGG PNHHLPLPDN WKSQVEPETR AVIRWMHSFN FVLSANLHGG AVVANYPYDK SFEHRVRGVR RTASTPTPDD KLFQKLAKVY SYAHGWMFQG WNCGDYFPDG ITNGASWYSL SKGMQDFNYL HTNCFEITLE LSCDKFPPEE ELQREWLGNR EALIQFLEQV HQGIKGMVLD ENYNNLANAV ISVSGINHDV TSGDHGDYFR LLLPGIYTVS ATAPGYDPET VTVTVGPAEP TLVNFHLKRS IPQVSPVRRA PSRRHGVRAK VQPQARKKEM EMRQLQRGPA (110-458 aa encoded by BC027897)
CPN1 is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The protein is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This protein is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Anaphylatoxin inactivator; Arginine carboxypeptidase; carboxypeptidase K; Carboxypeptidase N catalytic chain; carboxypeptidase N catalytic subunit; Carboxypeptidase N polypeptide 1; carboxypeptidase N polypeptide 1 50 kD; Carboxypeptidase N small subunit; carboxypeptidase N, polypeptide 1; carboxypeptidase N, polypeptide 1, 50kD; CPN; FLJ40792; kininase I; Kininase-1; Lysine carboxypeptidase; Plasma carboxypeptidase B; SCPN; Serum carboxypeptidase N
Gene Aliases: 0610011F20Rik; ACBP; CPN; CPN1; SCPN
Molecular Function: protease