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Proteintech
CPNE1 Polyclonal Antibody
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Product Details
10126-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CPNE1 Fusion Protein Ag0139 (25-289 aa encoded by BC001142)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KSDPLCVLL QDVGGGSWAE LGRTERVRNC SSPEFSKTLQ LEYRFETVQK LRFGIYDIDN KTPELRDDDF LGGAECSLGQ IVSSQVLTLP LMLKPGKPAG RGTITVSAQE LKDNRVVTME VEARNLDKKD FLGKSDPFLE FFRQGDGKWH LVYRSEVIKN NLNPTWKRFS VPVQHFCGGN PSTPIQVQCS DYDSDGSHDL IGTFHTSLAQ LQAVPAEFEC IHPEKQQKKK SYKNSGTIRV KICRVETEYS FLDYVMGGCQ INFTVG (25-289 aa encoded by BC001142)
Target Information
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Alternate splicing results in multiple transcript variants encoding different proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Chromobindin 17; Copine I; Copine-1; CPNE1; MGC1142; OTTHUMP00000030775; OTTHUMP00000030776
Gene Aliases: COPN1; CPN1; CPNE1
UniProt ID: (Human) Q99829
Entrez Gene ID: (Human) 8904
proteolysis
lipid metabolic process
negative regulation of gene expression
vesicle-mediated transport
cell differentiation
regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of DNA binding
positive regulation of neuron differentiation
positive regulation of protein kinase B signaling
cellular response to calcium ion
negative regulation of NIK/NF-kappaB signaling
positive regulation of tumor necrosis factor-mediated signaling pathway
neuron projection extension
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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