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Proteintech
CPOX Polyclonal Antibody
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Product Details
12211-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CPOX Fusion Protein Ag2858 (1-303 aa encoded by BC023551)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MALQLGRLS SGPCWLVARG GCGGPRAWSQ CGGGGLRAWS QRSAAGRVCR PPGPAGTEQS RGLGHGSTSR GGPWVGTGLA AALAGLVGLA TAAFGHVQRA EMLPKTSGTR ATSLGRPEEE EDELAHRCSS FMAPPVTDLG ELRRRPGDMK TKMELLILET QAQVCQALAQ VDGGANFSVD RWERKEGGGG ISCVLQDGCV FEKAGVSISV VHGNLSEEAA KQMRSRGKVL KTKDGKLPFC AMGVSSVIHP KNPHAPTIHF NYRYFEVEEA DGNKQWWFGG GCDLTPTYLN QEDAVHFHRT LKEA (1-303 aa encoded by BC023551)
Target Information
The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: clone 560; coprogen oxidase; Coproporphyrinogen III oxidase, mitochondrial precursor (Coproporphyrinogenase) (Coprogen oxidase) (COX); coproporphyrinogen-III oxidase, mitochondrial; coproporphyrinogenase; COX; cpox {ECO:0000312|EMBL:AAI07665.1}; Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
Gene Aliases: cac; CPO; CPOX; CPX; HCP; nct
UniProt ID: (Human) P36551, (Rat) Q3B7D0, (Mouse) P36552
Entrez Gene ID: (Human) 1371, (Rat) 304024, (Mouse) 12892
protoporphyrinogen IX biosynthetic process
heme biosynthetic process
response to iron ion
response to lead ion
response to insecticide
response to arsenic-containing substance
response to methylmercury
oxidation-reduction process
response to inorganic substance
porphyrin-containing compound biosynthetic process
potassium ion transport
sodium ion transport
sodium ion transmembrane transport
potassium ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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