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Product Details
16724-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000-1:5,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
CPOX Fusion Protein Ag10164 (95-454 aa encoded by BC017210) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.13 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: HVQRAEMLP KTSGTRATSL GRPEEEEDEL AHRCSSFMAP PVTDLGELRR RPGDMKTKME LLILETQAQV CQALAQVDGG ANFSVDRWER KEGGGGISCV LQDGCVFEKA GVSISVVHGN LSEEAAKQMR SRGKVLKTKD GKLPFCAMGV SSVIHPKNPH APTIHFNYRY FEVEEADGHK QWWFGGGCDL TPTYLNQEDA VHFHRTLKEA CDQHGPDLYP KFKKWCDDYF FIAHRGERRG IGGIFFDDLD SPSKEEVFRF VQSCARAVVP SYIPLVKKHC DDSFTPQEKL WQQLRRGRYV EFNLLYDRGT KFGLFTPGSR IESILMSLPL TARWEYMHSP SENSKEAEIL EVLRHPRDWV R (95-454 aa encoded by BC017210)
Target Information
The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: clone 560; coprogen oxidase; Coproporphyrinogen III oxidase, mitochondrial precursor (Coproporphyrinogenase) (Coprogen oxidase) (COX); coproporphyrinogen-III oxidase, mitochondrial; coproporphyrinogenase; COX; cpox {ECO:0000312|EMBL:AAI07665.1}; Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
Gene Aliases: cac; CPO; CPOX; CPX; HCP; nct
UniProt ID: (Human) P36551, (Rat) Q3B7D0, (Mouse) P36552
Entrez Gene ID: (Human) 1371, (Rat) 304024, (Mouse) 12892
Molecular Function:
oxidase
oxidoreductase
metabolite interconversion enzyme
protoporphyrinogen IX biosynthetic process
heme biosynthetic process
response to iron ion
response to lead ion
response to insecticide
response to arsenic-containing substance
response to methylmercury
oxidation-reduction process
response to inorganic substance
porphyrin-containing compound biosynthetic process
potassium ion transport
sodium ion transport
sodium ion transmembrane transport
potassium ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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