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          • Primary Antibodies ›
          • CPSF1 Antibodies

          Bethyl Laboratories

          CPSF160 Polyclonal Antibody

          View all (7) CPSF1 antibodies

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          Cite CPSF160 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (4)
          CPSF160 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          CPSF160 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          CPSF160 Antibody (IHC-00306) in IHC (P)

          Detection of human CPSF160 by IHC-IF. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-CPSF160 (Product # IHC-00306) used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody Hilyte Plus™ 555 used at a dilution of 1:100. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CPSF160 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CPSF160 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CPSF160 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CPSF160 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CPSF160 Polyclonal Antibody

          Product Details

          IHC-00306

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (IHC)

          1:50-1:500
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Region between residue 1392 and 1442 of human cleavage and polyadenylation specific factor 1, 160kD subunit.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.10 mg/mL

          Amount

          10 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          TBS, pH 7.0 to 8.0, with 0.1% BSA

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          The recommended shelf life for this product is 1 year from date of receipt.

          Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Horse, Guinea pig_10141, Pig, Panda, Orangutan, Monkey, Gorilla, Naked mole rat and Chinese hamster

          Target Information

          Midline-1 (Tripartite motif-containing protein 18, Putative transcription factor XPRF, RING finger protein 59) is a 667 amino acid protein encoded by the human gene MID1. Midline-1 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, one B30.2/SPRY domain, one COS domain, one fibronectin type-III domain and one RING-type zinc finger. Midline-1 is believed to have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation. It is a cytoplasmic protein found as a homodimer or heterodimer with Midline-2. It also interacts with IGBP1 (Lymphocyte signaling protein A4). Defects in MID1 are the cause of Opitz syndrome type I (OS-I). OS-I is an X-linked recessive disorder characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, lip-palate-laryngotracheal clefts, imperforate anus, developmental delay and congenital heart defects.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: cleavage and polyadenylation specific factor 1, 160kDa; cleavage and polyadenylation specificity factor 1; Cleavage and polyadenylation specificity factor 160 kDa subunit; Cleavage and polyadenylation specificity factor subunit 1; CPSF 160 kDa subunit; CPSF160; polyadenylation specificity factor; unnamed protein product

          View more View less

          Gene Aliases: CPSF1; CPSF160; HSU37012; MYP27; P/cl.18

          View more View less

          UniProt ID: (Human) Q10570, (Mouse) Q9EPU4

          View more View less

          Entrez Gene ID: (Human) 29894, (Mouse) 94230

          View more View less

          Function(s)
          nucleic acid binding RNA binding protein binding enzyme binding mRNA 3'-UTR AU-rich region binding mRNA binding mRNA 3'-UTR binding RNA processing factor
          Process(es)
          mRNA processing RNA 3'-end processing co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway mRNA polyadenylation mRNA cleavage
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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