Peptide sequence: TESTYATTIR DSKRCRERDF LKKVHETVER GGKGAHEPEG AHLLLHGADR
Sequence homology: Cow: 100%; Dog: 100%; Goat: 77%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.
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Protein Aliases: cleavage and polyadenylation specific factor 3-like; Cleavage and polyadenylation-specific factor 3-like protein; CPSF3-like protein; CPSF3L; Int11; Integrator complex subunit 11; integrator complex subunit 11-like; INTS11; Protein related to CPSF subunits of 68 kDa; RC-68; RC68; related to CPSF subunits 68 kDa
Gene Aliases: 2410006F12Rik; AU044035; BOS_16009; CPSF3L; CPSF73L; INT11; INTS11; RC-68; RC68; RGD1306841; zgc:110671