Immunogen sequence: LVGQAEPESV LLVHGEAKKM EFLKQKIEQE LRVNCYMPAN GETVTLPTSP SIPVGISLGL LKREMAQGLL PEAKKPRLLH GTLIMKDSNF RLVSSEQALK
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex.
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Protein Aliases: Cleavage and polyadenylation-specific factor 3-like protein; CPSF3-like protein; CPSF3L; Int11; Integrator complex subunit 11; INTS11; Protein related to CPSF subunits of 68 kDa; RC-68; RC68; related to CPSF subunits 68 kDa
Gene Aliases: 2410006F12Rik; AU044035; CPSF3L; CPSF73L; INT11; INTS11; RC-68; RC68; RGD1306841