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Immunogen sequence: MADGVDHID IYADVGEEFN QEAEYGGHDQ IDLYDDVISP SANNGDAPED RDYMDTLPPT VGDDVGKGAA PNVVYTYTGK RIALYIGNLT WWTTDEDLTE AVHSLGVNDI LEIKFFENRA NGQSKGFALV GVGSEASSKK LMDLLPKREL HGQNPVVTPC NKQFLSQFEM QSRKTTQSGQ MSGEGKAGPP GGSSRAAFPQ GGRGRGRFPG AVPGGDRFPG PAGPGGPPPP FPGNLIKHLV KGTRPLFLET RIPWHMGHSI EEIPIFGLKA GQTPPRPPLG PPGPPGPPGP PPPGQVLPPP LAGPPNRGDR PPPPVLFPGQ PFGQPPLGPL PPGPPPPVPG YGPPPGPPPP QQ (1-351 aa encoded by BC000714)
CPSF6 is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.
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Protein Aliases: CFIm68; cleavage and polyadenylation specific factor 6, 68kDa; Cleavage and polyadenylation specificity factor 68 kDa subunit; Cleavage and polyadenylation specificity factor subunit 6; Cleavage factor Im complex 68 kDa subunit; CPSF 68 kDa subunit; pre-mRNA cleavage factor I, 68kD subunit; pre-mRNA cleavage factor Im (68kD); Pre-mRNA cleavage factor Im 68 kDa subunit; Protein HPBRII-4/7
Gene Aliases: CFIM; CFIM68; CPSF6; HPBRII-4; HPBRII-7
UniProt ID: (Human) Q16630
Entrez Gene ID: (Human) 11052
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