Cellular retinoic acid binding protein (CRABP) is a low molecular weight protein with unknown function and existing in two isoforms, CRABP1 and CRABP2. The predicted amino acid sequences of human CRABP1 and CRABP2 exhibits 99.3 and 93.5% identity to mouse CRABP1 and CRABP2, respectively. The CRABP2 isoform is important in retinoic acid-mediated regulation of human skin growth and differentiation. The CRABP2 gene localized on human chromosome 1q21.3 is transcriptionally regulated by a newly synthesized regulatory protein. The protein is expressed in human adult liver.
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Protein Aliases: cellular lipid-binding protein; cellular retinoic acid binding protein II; Cellular retinoic acid-binding protein 2; Cellular retinoic acid-binding protein II; CRABP 2; CRABP II; CRABP-II; CRABP2; CRABPII
Gene Aliases: AI893628; Crabp-2; CRABP-II; CRABP2; CrabpII; RBP6