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Proteintech
CREB3L1/OASIS Polyclonal Antibody
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Product Details
11235-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CREB3L1,OASIS Fusion Protein Ag1757 (170-519 aa encoded by BC015781)
Conjugate
Form
Liquid
Concentration
0.28 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: PHQAPGEMT QLPVIKAEPL EVNQFLKVTP EDLVQMPPTP PSSHGSDSDG SQSPRSLPPS SPVRPMARSS TAISTSPLLT APHKLQGTSG PLLLTEEEKR TLIAEGYPIP TKLPLTKAEE KALKRVRRKI KNKISAQESR RKKKEYVECL EKKVETFTSE NNELWKKVET LENANRTLLQ QLQKLQTLVT NKISRPYKMA ATQTGTCLMV AALCFVLVLG SLVPCLPEFS SGSQTVKEDP LAADGVYTAS QMPSRSLLFY DDGAGLWEDG RSTLLPMEPP DGWEINPGGP AEQRPRDHLQ HDHLDSTHET TKYLSEAWPK DGGNGTSPDF SHSKEWFHDR DLGPNTTIKL S (170-519 aa encoded by BC015781)
Target Information
Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system. May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BBF-2 homolog; cAMP responsive element binding protein 3-like 1; cAMP-responsive element-binding protein 3-like protein 1; Cyclic AMP-responsive element-binding protein 3-like protein 1; OASIS; old astrocyte specifically induced substance; Old astrocyte specifically-induced substance
Gene Aliases: CREB3L1; OASIS; PSEC0238
UniProt ID: (Human) Q96BA8, (Mouse) Q9Z125, (Rat) Q66HA2
Entrez Gene ID: (Human) 90993, (Mouse) 26427, (Rat) 362165
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
protein binding
cAMP response element binding
sequence-specific DNA binding
transcription regulatory region DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
osteoblast differentiation
transcription from RNA polymerase II promoter
multicellular organism development
endoplasmic reticulum unfolded protein response
extracellular matrix constituent secretion
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
transcription, DNA-templated
regulation of transcription, DNA-templated
response to unfolded protein
regulation of ossification
positive regulation of transcription from RNA polymerase II promoter
regulation of bone mineralization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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