Immunogen sequence: DNEGALTSNWE QWDTYCEDLT KYTKLTSCDI WGTKEVDYLG LDDFSSPYQD EEVISKTPTL AQLNSEDSQS VSDSLYYPDS LFSVKQNPLP SSFPGKKITS RAAAPVCSSK TLQAEVPLSD CVQKASKPTS STQIMVKT
Highest antigen sequence identity to the following orthologs - mouse 96%, rat 96%.
Acts as a negative regulator of the endoplasmic reticulum stress response or unfolded protein response (UPR). Represses the transcriptional activity of CREB3 during the UPR. Recruits CREB3 into nuclear foci.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adult retina protein; CREB3 regulatory factor; LRF; Luman recruitment factor; luman-recruiting factor; luman/CREB3 recruitment factor; UPF0474 protein C5orf41
Gene Aliases: C5orf41; CREBRF; LRF
UniProt ID: (Human) Q8IUR6
Entrez Gene ID: (Human) 153222