This antibody is predicted to react with rat based on sequence homology.
XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chromosome region maintenance 1 homolog; Chromosome region maintenance 1 protein homolog; CRM1; Exp1; exportin 1 (CRM1 homolog, yeast); Exportin-1; exportin-1 (required for chromosome region maintenance); XPO1
Gene Aliases: AA420417; CRM1; emb; Exp1; XPO1
Molecular Function: receptor