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CRMP3 Antibody (MA5-44899) in WB
Western blot analysis of CRMP3 in different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. Samples were incubated in CRMP3 Monoclonal antibody (Product # MA5-44899) using a dilution of 1:2,000 in 5% BSA at room temperature for 2 hours followed by Goat Anti-Rabbit IgG - HRP secondary antibody at a dilution of 1:5,000 for 1 hour at room temperature. Positive control: Lane 1: Rat brain tissue lysate; Lane 2: Mouse hippocampus tissue lysate.
Product Details
MA5-44899
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JE56-59
Immunogen
Recombinant protein within human CRMP3 aa 1-100.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2931355
Target Information
Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Collapsin response mediator protein 3; CRMP-3; dihydropyrimidinase-like 4; Dihydropyrimidinase-related protein 4; DRP-4; ULIP-4; ULIP4 protein; unc-33-like phosphoprotein 4; UNC33-like phosphoprotein 4
Gene Aliases: AI173505; CRMP-3; CRMP3; DPY4; Dpys4; DPYSL4; DRP-4; ULIP4
UniProt ID: (Human) O14531, (Rat) Q62951
Entrez Gene ID: (Human) 10570, (Rat) 25417, (Mouse) 26757
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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