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Proteintech
CRMP5 Polyclonal Antibody
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Product Details
10525-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CRMP5 Fusion Protein Ag0783 (265-564 aa encoded by BC002874)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KVVLAETTT AHATLTGLHY YHQDWSHAAA YVTVPPLRLD TNTSTYLMSL LANDTLNIVA SDHRPFTTKQ KAMGKEDFTK IPHGVSGVQD RMSVIWERGV VGGKMDENRF VAVTSSNAAK LLNLYPRKGR IIPGADADVV VWDPEATKTI SASTQVQGGD FNLYENMRCH GVPLVTISRG RVVYENGVFM CAEGTGKFCP LRSFPDTVYK KLVQREKTLK VRGVDRTPYL GDVAVVVHPG KKEMGTPLAD TPTRPVTRHG GMRDLHESSF SLSGSQIDDH VPKRASARIL APPGGRSSGI W (265-564 aa encoded by BC002874)
Target Information
The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence homology with the other four members of the CRMP family. CRMP5 is expressed in the developing nervous system in an expression pattern that resembles CRMP2 and has a peak expression during the first postnatal week. Elevated levels of autoantibody to CRMP5 have been shown to be linked to paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms. Auto-immunity against CRMP5 expression (predominantly the N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and in the thymus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Collapsin response mediator protein 5; collapsin response mediator protein-5; CRAM; CRMP-5; CRMP3-associated molecule; dihydropyrimidinase-like 5; Dihydropyrimidinase-related protein 5; DRP-5; ULIP-6; ULIP6 protein; UNC33-like phosphoprotein 6
Gene Aliases: CRAM; CRMP-5; CRMP5; DPYSL5; ULIP6
UniProt ID: (Human) Q9BPU6, (Rat) Q9JHU0, (Mouse) Q9EQF6
Entrez Gene ID: (Human) 56896, (Rat) 65208, (Mouse) 65254
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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