This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: VRWGDKSYNL ISFSNGVFGC NCDHAPFDAM IMVNISYYVD EKIFQNEGRW KGSEKVRDIP LPEELIFIVD EKVLNDINQA KAQYLR
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 79%.
CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4, 8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: COT; peroxisomal carnitine acyltransferase; Peroxisomal carnitine O-octanoyltransferase
Gene Aliases: COT; CROT
UniProt ID: (Human) Q9UKG9
Entrez Gene ID: (Human) 54677