Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: VYGNWNGPH RLYLQMSTHG KVRFRDIASP KFSMPSPVRT VITADFDNDQ ELEIFFNNIA YRSSSANRLF RVIRREHGDP LIEELNPGDA LEPEGRGTGG VVTDFDGDGM LDLILSHGES MAQPLSVFRG NQGFNNNWLR VVPRTRFGAF ARGAKVVLYT KKSGAHLRII DGGSGYLCEM EPVAHFGLGK DEASSVEVTW PDGKMVSRNV ASGEMNSVLE ILYPRDEDTL QDPAPLECGQ GFSQQENGHC MDTNECIQFP FVCPRDKPVC VNTYGSYRCR TNKKCSRGYE PNEDGTACVG TLGQSPGPRP TTPTAAAATA AAAAAAGAAT AAPVLVDGDL NLGSVVKESC EPSC (99-451 aa encoded by BC034245)
CRTAC1 encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 68 kDa chondrocyte-expressed protein; acidic secreted protein in cartilage; ASPIC; Cartilage acidic protein 1; CEP-68; chondrocyte expressed protein 68 kDa CEP-68; FLJ10320; Protein CRTAC1-B
Gene Aliases: 2810454P21Rik; ASPIC; ASPIC1; AW047536; CEP-68; CEP68; CRTAC1; Crtac1B; Lotus; W307
UniProt ID: (Human) Q9NQ79, (Mouse) Q8R555
Entrez Gene ID: (Human) 55118, (Mouse) 72832, (Rat) 171438
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