Recommended positive controls: A431.
Predicted reactivity: Mouse (94%), Rhesus Monkey (99%), Chimpanzee (98%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cartilage-associated protein; leprecan-like 3; prolyl 3-hydroxylase family member 5 (non-enzymatic)
Gene Aliases: CASP; CRTAP; LEPREL3; OI7; P3H5
UniProt ID: (Human) O75718
Entrez Gene ID: (Human) 10491
Molecular Function: extracellular matrix protein