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Invitrogen
CRTC3 Monoclonal Antibody (R.185.4)
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 6
CRTC3 Antibody (MA5-14919) in ICC/IF
Immunofluorescence analysis of Torc3 was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with anti-Torc3 Rabbit Monoclonal Antibody (Product # MA5-14919) at 1:200 dilution in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (P... View More
Product Details
MA5-14919
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Monoclonal
Type
Antibody
Clone
R.185.4
Immunogen
Synthetic peptide corresponding to the sequence of human TORC3 (CRTC3) protein
Conjugate
Form
Liquid
Concentration
168 µg/mL
Purification
Affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
<0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_10979546
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The protein encoded by this gene has similarity to a yeast protein. It seems to be part of a peripheral membrane protein complex localized on cis/medial Golgi cisternae where it may participate in tethering intra-Golgi transport vesicles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CREB regulated transcription coactivator 3; CREB-regulated transcription coactivator 3; TORC-3; transducer of CREB protein 3; transducer of regulated cAMP response element-binding protein (CREB) 3; Transducer of regulated cAMP response element-binding protein 3; transducer of regulated CREB protein 3
Gene Aliases: 2610312F20Rik; 6332415K15Rik; AI429792; BC011210; CRTC3; RGD1309666; TORC-3; TORC3
UniProt ID: (Human) Q6UUV7, (Mouse) Q91X84
Entrez Gene ID: (Human) 64784, (Mouse) 70461, (Rat) 365297
transcription, DNA-templated
viral process
positive regulation of CREB transcription factor activity
macrophage activation
negative regulation of cAMP-mediated signaling
positive regulation of transcription from RNA polymerase II promoter
negative regulation of lipid catabolic process
protein homotetramerization
energy homeostasis
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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