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Invitrogen
CRTC3 Monoclonal Antibody (R.185.4)
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 6
CRTC3 Antibody (MA5-14919) in WB
Western blot analysis was performed on whole cell extracts (30 µg lysate) of Hela (Lane 1), A431 (Lane 2) U2OS (Lane 3), HEK293 (Lane 4), Jurkat (Lane 5), COS-7 (Lane 6) and MCF-7 (Lane 7). The blot was probed with Anti-Torc3 Monoclonal Antibody (Product # MA5-14919, 1:1000 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (H+L) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4000 dilution). A 67 kDa band corresponding to Torc3 was observed in HeLa, U2OS and HEK293 when compared to other... View More
Product Details
MA5-14919
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Monoclonal
Type
Antibody
Clone
R.185.4
Immunogen
Synthetic peptide corresponding to the sequence of human TORC3 (CRTC3) protein
Conjugate
Unconjugated
Form
Liquid
Concentration
168 µg/mL
Purification
Affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
<0.02% sodium azide
Storage conditions
-20°C
RRID
AB_10979546
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The protein encoded by this gene has similarity to a yeast protein. It seems to be part of a peripheral membrane protein complex localized on cis/medial Golgi cisternae where it may participate in tethering intra-Golgi transport vesicles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CREB regulated transcription coactivator 3; CREB-regulated transcription coactivator 3; TORC-3; transducer of CREB protein 3; transducer of regulated cAMP response element-binding protein (CREB) 3; Transducer of regulated cAMP response element-binding protein 3; transducer of regulated CREB protein 3
Gene Aliases: 2610312F20Rik; 6332415K15Rik; AI429792; BC011210; CRTC3; RGD1309666; TORC-3; TORC3
UniProt ID: (Human) Q6UUV7, (Mouse) Q91X84
Entrez Gene ID: (Human) 64784, (Mouse) 70461, (Rat) 365297
Molecular Function:
transcription cofactor
transcription, DNA-templated
viral process
positive regulation of CREB transcription factor activity
macrophage activation
negative regulation of cAMP-mediated signaling
positive regulation of transcription from RNA polymerase II promoter
negative regulation of lipid catabolic process
protein homotetramerization
energy homeostasis
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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