In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Pig (85%) Elephant (80%).
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthama susceptibility.
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Protein Aliases: CD294; chemoattractant receptor homologous molecule expressed on T helper type 2 cells; Chemoattractant receptor-homologous molecule expressed on Th2 cells; CRTH2; DL1R; DP2; G Protein-Coupled Rec. 44; G protein-coupled receptor 44; G-protein coupled receptor 44; GPR44; Prostaglandin D2 receptor 2; putative G-protein coupled receptor 44
Gene Aliases: CD294; CRTH2; DL1R; DP2; GPR44; PTGDR2
UniProt ID: (Human) Q9Y5Y4
Entrez Gene ID: (Human) 11251