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Invitrogen
CRYGF Polyclonal Antibody
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Product Details
PA5150167
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Crystallin Gamma F (CRYgF) (Met1-Phe173)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The CRYGF gene, part of the gammacrystallin gene family, is critical for maintaining lens transparency in the eye. Located on mouse chromosome 1, the CRYGF gene, along with its related gammacrystallin counterparts, contributes significantly to lens function and clarity. Mutations within this gene can lead to cataracts, a clouding of the lens, and are thus crucial for understanding hereditary cataract formation. The dominant mutation known as Crygf(Rop) has been identified, underscoring the gene's role in lens transparency and highlighting the genetic and allelic heterogeneity present within the gammacrystallin family. Although fewer mutations have been discovered in CRYGF compared to other gammacrystallins, its importance remains substantial in the lens' structural integrity and optical properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CRYGF; crystallin, gamma polypeptide 6; gamma-crystallin 4-1; Gamma-crystallin F; Gamma-F-crystallin
Gene Aliases: 3110001K11Rik; Cryg-2; Cryg6; Crygf; DGcry-2; Len; Len-2
UniProt ID: (Mouse) Q9CXV3
Entrez Gene ID: (Rat) 689947, (Mouse) 12969
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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