This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: YEIFTEQFSFK EVRIWNRTKE NAEKFADTVQ GEVRVCSSVQ EAVAGADVII TVTLATEPIL FGEWVKPGAH INAVGASRPD WRE
Highest antigen sequence identity to the following orthologs - mouse 93%, rat 92%.
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Multiple alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: crystallin, mu; DFNA40; ketimine reductase; Ketimine reductase mu-crystallin; mu-crystallin homolog; NADP-regulated thyroid-hormone binding protein; NADP-regulated thyroid-hormone-binding protein; THBP; thiomorpholine-carboxylate dehydrogenase
Gene Aliases: CRYM; DFNA40; THBP
UniProt ID: (Human) Q14894
Entrez Gene ID: (Human) 1428
Molecular Function: lyase