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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD116 antigen, GM-CSF receptor alpha subunit, GMCSFR-alpha, GMR-alpha, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), granulocyte-macrophage colony-stimulating factor receptor alpha chain, CD116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GMCSFR, GMR, MGC3848, MGC4838
CSF2R, CSF2RX, CSF2RY, GMCSFR, CSF2RAY, CDw116, CD116, CSF2RAX, GM-CSF-R-alpha, SMDP4, GMR
Signal transduction Cell surface receptor mediated signal transduction Cytokine and chemokine mediated signaling pathway Intracellular signaling cascade JAK-STAT cascade Cell communication Ligand-mediated signaling Immunity and defense Granulocyte-mediated immunity Apoptosis Inhibition of apoptosis