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CSNK1A1/CK1 is a casein kinase. These kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins including CTNNB1, PER1, and PER2. CSNK1A1 also participates in Wnt signaling. It may play a role in segregating chromosomes during mitosis, as well as, cytoskeleton diassembly which may regulate epithelial cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: casein kinase 1, alpha 1-like; casein kinase I alpha S-like; Casein kinase I isoform alpha-like; CK1; CKI-alpha-like
Gene Aliases: CK1; CSNK1A1L
UniProt ID: (Human) Q8N752
Entrez Gene ID: (Human) 122011
Molecular Function:
kinase
non-receptor serine/threonine protein kinase
protein kinase
transferase
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