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Proteintech
CSNK2A1 Polyclonal Antibody
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Product Details
10992-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CSNK2A1 Fusion Protein Ag1452 (1-391 aa encoded by BC011668)
Conjugate
Form
Liquid
Concentration
0.62 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSGPVPSRA RVYTDVNTHR PREYWDYESH VVEWGNQDDY QLVRKLGRGK YSEVFEAINI TNNEKVVVKI LKPVKKKKIK REIKILENLR GGPNIITLAD IVKDPVSRTP ALVFEHVNNT DFKQLYQTLT DYDIRFYMYE ILKALDYCHS MGIMHRDVKP HNVMIDHEHR KLRLIDWGLA EFYHPGQEYN VRVASRYFKG PELLVDYQMY DYSLDMWSLG CMLASMIFRK EPFFHGHDNY DQLVRIAKVL GTEDLYDYID KYNIELDPRF NDILGRHSRK RWERFVHSEN QHLVSPEALD FLDKLLRYDH QSRLTAREAM EHPYFYTVVK DQARMGSSSM PGGSTPVSSA NMMSGISSVP TPSPLGPLAG SPVIAAANPL GMPVPAAAGA QQ (1-391 aa encoded by BC011668)
Target Information
CSNK2A1 is a serine/threonine protein kinase that phosphorylates acidic proteins. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by CK2 alpha-1 represents the alpha subunit. While CK2 alpha-1 is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for CK2 alpha-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: casein kinase 2 alpha; casein kinase 2, alpha 1 polypeptide; casein kinase II alpha 1 polypeptide pseudogene; casein kinase II alpha 1 subunit; Casein kinase II subunit alpha; casein kinase II, alpha 1 polypeptide; casein kinase II, alpha 1 related sequence 4; CK II alpha; CK II alpha 3; CK2 catalytic subunit alpha; protein kinase CK2
Gene Aliases: CK2A1; CKII; Ckiia; CSNK2A1; Csnk2a1-rs4; CSNK2A3
UniProt ID: (Human) P68400, (Mouse) Q60737, (Rat) P19139
Entrez Gene ID: (Human) 1457, (Mouse) 12995, (Rat) 116549
protein phosphorylation
positive regulation of cell proliferation
positive regulation of Wnt signaling pathway
positive regulation of cell growth
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of protein catabolic process
protein autophosphorylation
regulation of catalytic activity
mitotic spindle checkpoint
regulation of cell growth
transcription, DNA-templated
regulation of transcription, DNA-templated
Wnt signaling pathway
regulation of cell proliferation
rhythmic process
protein folding
apoptotic process
signal transduction
chaperone-mediated protein folding
regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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