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OriGene
CSNK2B Polyclonal Antibody
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FIGURE: 1 / 2
CSNK2B Antibody (TA890031) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CSNK2B(RC211299, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CSNK2B. Positive lysates LY400525 (100 µg) and LC400525 (20 µg) can be purchased separately from OriGene.
Product Details
TA890031
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein of human CSNK2B
Conjugate
Form
Liquid
Concentration
1.42 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alternative name: G5a, phosvitin; casein kinase 2, beta polypeptide; casein kinase 2, beta subunit; casein kinase II b subunit splicing isoform 132; casein kinase II b subunit splicing isoform 247; casein kinase II b subunit splicing isoform 318; casein kinase II b subunit splicing isoform 660; casein kinase II b subunit splicing isoform 806; Casein kinase II beta subunit; Casein kinase II subunit beta; chimera CSNK2B-LY6G5B splicing isoform 1072; chimera CSNK2B-LY6G5B splicing isoform 1103; chimera Csnk2b-Ly6g5b splicing isoform 2050; chimera Csnk2b-Ly6g5b splicing isoform 2275; chimera Csnk2b-Ly6g5b splicing isoform 2531; chimera CSNK2B-LY6G5B splicing isoform 532; chimera CSNK2B-LY6G5B splicing isoform 560; chimera CSNK2B-LY6G5B splicing isoform 562; chimera Csnk2b-Ly6g5b splicing isoform 901; CK II beta; Csnk2b splicing isoform 280; Csnk2b splicing isoform 662; Csnk2b-Ly6g5b; CSNK2B-LY6G5B-1072; CSNK2B-LY6G5B-1103; CSNK2B-LY6G5B-532; CSNK2B-LY6G5B-560; CSNK2B-LY6G5B-562; DADB-127H9.2; MGC138222; MGC138224; Phosvitin; Protein G5a
Gene Aliases: CK II beta; Ck2; CK2B; CK2N; CSK2B; CSNK2B; G5A
UniProt ID: (Human) P67870, (Rat) P67874, (Mouse) P67871
Entrez Gene ID: (Human) 1460, (Rat) 81650, (Mouse) 13001
protein folding
protein phosphorylation
signal transduction
negative regulation of cell proliferation
positive regulation of pathway-restricted SMAD protein phosphorylation
Wnt signaling pathway
positive regulation of activin receptor signaling pathway
adiponectin-activated signaling pathway
negative regulation of blood vessel endothelial cell migration
cellular protein complex assembly
regulation of protein kinase activity
regulation of DNA binding
endothelial tube morphogenesis
regulation of signal transduction by p53 class mediator
I-kappaB kinase/NF-kappaB signaling
positive regulation of Wnt signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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