This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: YQARKKTFLS VHEVMAVENY AKDSLQWITD QYNKESDDKY HFRIFRV
Highest antigen sequence identity to the following orthologs: Mouse - 49%, Rat - 49%.
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes an epididymal-specific protein shown to have antimicrobial activity against E. coli. Alternative splicing yields two variants encoding distinct isoforms. [provided by RefSeq, Sep 2014].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CST8L; Cystatin-11; cystatin-related epididymal-specific protein; dJ322G13.6; SC13; SC13delta
Gene Aliases: CST11; CST8L; CTES2; dJ322G13.6; SC13
UniProt ID: (Human) Q9H112
Entrez Gene ID: (Human) 140880