Immunogen sequence: QLWRDYNKYE EGINIHLAKK MIEDRSRDYM NARRVAKEYE TVMKGLDRNA PSVPPQNTPQ EAQQVDMWKK YIQWEKSNPL RTEDQTLITK RVMFAYEQCL LVLGHH
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.
The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CF-1 77 kDa subunit; Cleavage stimulation factor 77 kDa subunit; Cleavage stimulation factor subunit 3; cleavage stimulation factor subunit 3, isoform 1; cleavage stimulation factor, 3' pre-RNA, subunit 3; cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kD; cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa; CSTF 77 kDa subunit; MGC117398; MGC43001; MGC75122
Gene Aliases: 4732468G05Rik; C79532; CSTF-77; CSTF3