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Product Details
PA5-103697
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000-1:3,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthesized peptide derived from human CTAG2(Accession O75638), corresponding to amino acid residues M135-S159. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2853030 |
Target Information
CTAG2 encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Autoimmunogenic cancer/testis antigen NY-ESO-2; Cancer/testis antigen 2; Cancer/testis antigen 6.2; cancer/testis antigen family 6, member 2a; cancer/testis antigen family 6, member 2b; CT2; CT6.2; CTL-recognized antigen on melanoma; L antigen family member 1; LAGE-1; LAGE-1a protein
Gene Aliases: CAMEL; CT2; CT6.2; CT6.2a; CT6.2b; CTAG2; ESO2; LAGE-1; LAGE1; LAGE2B; RGD1561702
UniProt ID: (Human) O75638
Entrez Gene ID: (Human) 30848, (Rat) 501655
Performance Guarantee
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