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Proteintech
CTBP2 Polyclonal Antibody
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Product Details
10346-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Gerbil,
Mouse,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CTBP2 Fusion Protein Ag0352 (24-201 aa encoded by BC002486)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: QIMNGPLHP RPLVALLDGR DCTVEMPILK DLATVAFCDA QSTQEIHEKV LNEAVGAMMY HTITLTREDL EKFKALRVIV RIGSGYDNVD IKAAGELGIA VCNIPSAAVE ETADSTICHI LNLYRRNTWL YQALREGTRV QSVEQIREVA SGAARIRGET LGLIGFGRTG QAVAVRAKA (24-201 aa encoded by BC002486)
Target Information
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21. 3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C-terminal-binding protein 2; CTBP2; gene trap ROSA b-geo 6; phosphoprotein; CtBP; transcriptional corepressor; ribeye; RP11-59C5.2; unnamed protein product
Gene Aliases: AA407280; CTBP2; D7Ertd45e; Gtrgeo6; Ribeye
UniProt ID: (Human) P56545, (Rat) Q9EQH5, (Mouse) P56546
Entrez Gene ID: (Human) 1488, (Rat) 81717, (Mouse) 13017
transcription cofactor binding
transcription corepressor binding
transcription coactivator activity
transcription corepressor activity
protein binding
oxidoreductase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
protein kinase binding
identical protein binding
macromolecular complex binding
NAD binding
DNA-binding transcription factor binding
chromatin binding
retinoic acid receptor binding
transcription cofactor
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
negative regulation of cell proliferation
viral genome replication
cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of retinoic acid receptor signaling pathway
white fat cell differentiation
transcription, DNA-templated
positive regulation of chromatin binding
oxidation-reduction process
regulation of transcription, DNA-templated
metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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