Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
CTGF Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
23903-1-AP
Applications
Tested Dilution
Publications
Immunoprecipitation (IP)
0.5-4.0 µg for 1.0-3.0 mg of total protein lysate
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CTGF fusion protein Ag20985
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: LFCDFGSPAN RKIGVCTAKD GAPCIFGGTV YRSGESFQSS CKYQCTCLDG AVGCMPLCSM DVRLPSPDCP FPRRVKL
Target Information
Connective Tissue Growth Factor (CTGF), also called CCN2, is a member of the CCN family. CTGF is a secreted protein produced by umbilical veins and vascular endothelial cells. CTGF possesses an Insulin-like Growth Factor (IGF)-binding domain, a thrombospondin type 1 domain, and a cysteine knot region. CTGF plays important roles in the proliferation and differentiation of chondrocytes, induces angiogenesis, and promotes cell adhesion in fibroblasts, endothelial, and epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 2-Nov; CCN family member 2; Cellular communication network factor 2; Connective tissue growth factor; Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24); fibroblast inducible secreated protein; fibroblast inducible secreted protein; H-CTGF; hypertrophic chondrocyte-specific gene product 24; Hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; Insulin-like growth factor-binding protein 8; MGC102839; Protein FISP-12
Gene Aliases: betaIG-M2; CCN2; CTGF; Fisp-12; Fisp12; HCS24; IGFBP8; NOV2
UniProt ID: (Human) P29279, (Mouse) P29268
Entrez Gene ID: (Human) 1490, (Mouse) 14219
cartilage condensation
ossification
angiogenesis
regulation of cell growth
tissue homeostasis
transcription initiation from RNA polymerase II promoter
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
cell-cell signaling
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
epidermis development
response to wounding
response to glucose
organ senescence
positive regulation of gene expression
negative regulation of gene expression
cell migration
cell differentiation
lung development
regulation of chondrocyte differentiation
response to estradiol
positive regulation of collagen biosynthetic process
response to anoxia
intracellular signal transduction
chondrocyte proliferation
response to amino acid
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to peptide hormone
positive regulation of cell differentiation
positive regulation of JNK cascade
positive regulation of cell activation
response to mineralocorticoid
positive regulation of stress fiber assembly
cytosolic calcium ion transport
positive regulation of cardiac muscle contraction
negative regulation of cell death
extracellular matrix constituent secretion
positive regulation of G0 to G1 transition
positive regulation of ERK1 and ERK2 cascade
response to fatty acid
DNA biosynthetic process
reactive oxygen species metabolic process
positive regulation of protein phosphorylation
positive regulation of cell death
connective tissue development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support