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CTGF Polyclonal Antibody

View all (38) CTGF antibodies

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CTGF Polyclonal Antibody

Product Details

BS-0743R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human CTGF, amino acids 221-349.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Connective Tissue Growth Factor (CTGF), also called CCN2, is a member of the CCN family. CTGF is a secreted protein produced by umbilical veins and vascular endothelial cells. CTGF possesses an Insulin-like Growth Factor (IGF)-binding domain, a thrombospondin type 1 domain, and a cysteine knot region. CTGF plays important roles in the proliferation and differentiation of chondrocytes, induces angiogenesis, and promotes cell adhesion in fibroblasts, endothelial, and epithelial cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 2-Nov; CCN family member 2; Cellular communication network factor 2; Connective tissue growth factor; Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24); Connective tissue growth-related protein; CTGF; fibroblast inducible secreated protein; fibroblast inducible secreted protein; H-CTGF; hypertrophic chondrocyte-specific gene product 24; Hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; Insulin-like growth factor-binding protein 8; MGC102839; Protein FISP-12; unnamed protein product

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Gene Aliases: betaIG-M2; CCN2; CTGF; CTGRP; Fisp-12; Fisp12; HCS24; IBP-8; IGFBP8; KMD; NOV2; SEMDLSL

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UniProt ID: (Human) P29279, (Mouse) P29268, (Rat) Q9R1E9

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Entrez Gene ID: (Human) 1490, (Mouse) 14219, (Rat) 64032

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Function(s)
integrin binding protein binding insulin-like growth factor binding heparin binding fibronectin binding growth factor activity growth factor
Process(es)
cartilage condensation ossification angiogenesis osteoblast differentiation tissue homeostasis chondrocyte differentiation cell adhesion cell-matrix adhesion signal transduction integrin-mediated signaling pathway fibroblast growth factor receptor signaling pathway epidermis development response to wounding negative regulation of gene expression cell migration lung development regulation of chondrocyte differentiation chondrocyte proliferation positive regulation of cell differentiation positive regulation of JNK cascade regulation of developmental process positive regulation of stress fiber assembly connective tissue development positive regulation of ERK1 and ERK2 cascade DNA biosynthetic process reactive oxygen species metabolic process regulation of cell growth positive regulation of protein phosphorylation cell-cell signaling positive regulation of cell proliferation positive regulation of gene expression positive regulation of cell death cell differentiation positive regulation of collagen biosynthetic process intracellular signal transduction positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of cell activation cytosolic calcium ion transport positive regulation of cardiac muscle contraction negative regulation of cell death extracellular matrix constituent secretion positive regulation of G0 to G1 transition response to glucose organ senescence response to organic cyclic compound response to estradiol response to anoxia response to amino acid response to peptide hormone response to mineralocorticoid response to fatty acid
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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