PA5-32193 targets CTGF in IHC (P) and WB applications and shows reactivity with Human, mouse, and Rat samples.
The PA5-32193 immunogen is recombinant fragment corresponding to a region within amino acids 115 and 315 of Human CTGF.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis.
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Protein Aliases: CCN family member 2; CCN2; Connective tissue growth factor; Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24); Connective tissue growth-related protein; fibroblast inducible secreated protein; fibroblast inducible secreted protein; HCS24; hypertrophic chondrocyte-specific gene product 24; Hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; IGFBP8; Insulin-like growth factor-binding protein 8; NOV2; Protein FISP-12
Gene Aliases: CCN2; CTGF; CTGRP; Fisp-12; Fisp12; HCS24; IGFBP8; NOV2