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This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
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Protein Aliases: Cystathionine gamma-lyase; Cysteine-protein sulfhydrase; Gamma-cystathionase; MGC9471
Gene Aliases: 0610010I13Rik; AI314617; BC019483; CSE; Cth; Cys3
UniProt ID: (Mouse) Q8VCN5
Entrez Gene ID: (Mouse) 107869
Molecular Function: lyase