Reconstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein receptor that down regulates the immune system. It is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Blockade of CTLA4 expression in vitro augmented HIV-specific CD4-positive T-cell function.
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Protein Aliases: CD152; CD152 antigen; CTLA-4; Ctla4; Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; soluble form; transmembrane form
Gene Aliases: Cd152; CTLA-4; Ctla4; Ly-56; sCTLA4
UniProt ID: (Mouse) P09793