Proteintech

CTNS Polyclonal Antibody

Product Image Gallery

CTNS Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of ( -20°C Ethanol ) fixed HEK-293 cells using 13085-1-AP (CTNS antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

CTNS Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human pancreas cancer using 13085-1-AP (CTNS antibody) at dilution of 1:100 (under 10x lens).

CTNS Antibody in Western Blot (WB) — HEK-293 cells were subjected to SDS PAGE followed by western blot with 13085-1-AP (CTNS antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Product Details

13085-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	-
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	1:50-1:500	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	CTNS Fusion Protein Ag3904 (24-170 aa encoded by BC032850) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.17 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.1% sodium azide
Storage conditions	-20°C

Product Specific Information

This antibody was raised against the N-terminal region of human cystinosin. Two isoforms of CTNS exist due to alternative splicing events and both of them can be detected through this antibody.

Immunogen sequence: VSLTVPPVV KLENGSSTNV SLTLRPPLNA TLVITFEITF RSKNITILEL PDEVVVPPGV TNSSFQVTSQ NVGQLTVYLH GNHSNQTGPR IRFLVIRSSA ISIINQVIGW IYFVAWSISF YPQVIMNWRR KSVIGLSFDF VALNLTGF (24-170 aa encoded by BC032850 )

Target Information

This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.