Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
The recommended shelf life for this product is 1 year from date of receipt.
The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CTP synthase 2; CTP synthase II; CTP synthetase 2; CTP synthetase type 2; cytidine 5'-triphosphate synthetase 2; UTP--ammonia ligase 2; UTP-ammonia ligase 2
Gene Aliases: CTPS2
UniProt ID: (Human) Q9NRF8
Entrez Gene ID: (Human) 56474
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