This CTR2 antibody is useful for Western blot, where a band is seen at ~71 kDa.
The theoretical molecular weight of CTR2 is 15 kDa.
The difference between the expected size and the observed size in Western blot is believed to be due to a multimeric form of CTR2.Suggested positive control: MEF whole cell lysate.
Copper is a trace element that plays an essential role for organisms that utilize oxygen during respiration. CTR2 is a membrane protein that is a member of the SLC31A transporter family. Although the function of CTR2 is still poorly understood in mammalian cells, it is expected to be involved in low-affinity copper uptake. It is believed to be confined to lysosomes which stimulate copper delivery to the the cytosol of human cells at high concentrations.
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Protein Aliases: Copper transporter 2; CTR2; hCTR2; Probable low affinity copper uptake protein 2; RP11-9H12.2; solute carrier family 31 (copper transporter), member 2; solute carrier family 31 (copper transporters), member 2; Solute carrier family 31 member 2
Gene Aliases: AI604396; COPT2; CTR2; hCTR2; SLC31A2