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Bethyl Laboratories
CTR9 Polyclonal Antibody
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Product Details
IHC-00288
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1123 and 1173 of human Paf1/RNA polymerase II complex component homolog CTR9.
Conjugate
Form
Liquid
Concentration
50 µg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon and Little brown bat
Target Information
MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ctr9, Paf1/RNA polymerase II complex component, homolog; KIAA0155; p150TSP; RNA polymerase-associated protein CTR9 homolog; SH2 domain binding protein 1 (tetratricopeptide repeat containing); SH2 domain-binding protein 1; Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa; TPR-containing, SH2-binding phosphoprotein; TPR-containing, SH2-binding phosphoprotein of 150 kDa; unnamed protein product
Gene Aliases: AA409336; CTR9; KIAA0155; mKIAA0155; p150; p150TSP; SH2BP1; TSBP; Tsp
UniProt ID: (Human) Q6PD62, (Mouse) Q62018
Entrez Gene ID: (Human) 9646, (Mouse) 22083
negative regulation of transcription from RNA polymerase II promoter
endodermal cell fate commitment
inner cell mass cell differentiation
trophectodermal cell differentiation
blastocyst growth
blastocyst hatching
chromatin organization
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
JAK-STAT cascade
Wnt signaling pathway
stem cell population maintenance
negative regulation of myeloid cell differentiation
negative regulation of gene expression, epigenetic
positive regulation of transcription from RNA polymerase II promoter
interleukin-6-mediated signaling pathway
cellular response to lipopolysaccharide
transcription, DNA-templated
histone monoubiquitination
positive regulation of transcription elongation from RNA polymerase II promoter
histone H2B ubiquitination
positive regulation of histone H3-K4 methylation
histone H3-K4 trimethylation
negative regulation of mRNA polyadenylation
regulation of genetic imprinting
positive regulation of histone H3-K79 methylation
positive regulation of histone H2B ubiquitination
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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