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Proteintech
CTRP1 Polyclonal Antibody
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Product Details
12209-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CTRP1 Fusion Protein Ag2854 (1-281 aa encoded by BC021553)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MGSRGQGLL LAYCLLLAFA SGLVLSRVPH VQGEQQEWEG TEELPSPPDH AERAEEQHEK YRPSQDQGLP ASRCLRCCDP GTSMYPATAV PQINITILKG EKGDRGDRGL QGKYGKTGSA GARGHTGPKG QKGSMGAPGE RCKSHYAAFS VGRKKPMHSN HYYQTVIFDT EFVNLYDHFN MFTGKFYCYV PGLYFFSLNV HTWNQKETYL HIMKNEEEVV ILFAQVGDRS IMQSQSLMLE LREQDQVWVR LYKGERENAI FSEELDTYIT FSGYLVKHAT EP (1-281 aa encoded by BC021553)
Target Information
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C1q and tumor necrosis factor related protein 1; Complement C1q tumor necrosis factor-related protein 1; G protein coupled receptor interacting protein; G protein-coupled receptor-interacting protein; GIP; unnamed protein product
Gene Aliases: C1QTNF1; CTRP1; GIP; UNQ310/PRO353; ZSIG37
UniProt ID: (Human) Q9BXJ1
Entrez Gene ID: (Human) 114897
positive regulation of cytosolic calcium ion concentration
negative regulation of platelet activation
positive regulation of gene expression
regulation of glucose metabolic process
positive regulation of MAPK cascade
positive regulation of protein kinase B signaling
negative regulation of platelet aggregation
positive regulation of aldosterone secretion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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