This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: CQRCCDSEDP LDPAHVSSAS SSGRPHALPE IRPYINITIL KGDKGDPGPM GLPGYMGREG PQGEPGPQGS KGDKGEMGSP GAPCQKRFFA FSVGRKTALH SGEDFQTLLF ERVFVNLDGC FDMATGQFAA PLR
Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 66%.
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP6 contains at least 4 glycosylation motifs, suggesting that CTRP6 may be highly post-translationally modified.
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Protein Aliases: Complement C1q tumor necrosis factor-related protein 6; complement-c1q tumor necrosis factor-related protein 6
Gene Aliases: C1QTNF6; CTFP6; CTRP6; UNQ581/PRO1151; ZACRP6
UniProt ID: (Human) Q9BXI9
Entrez Gene ID: (Human) 114904