Product References
Proteomic analysis of DZIP3 interactome and its role in proliferation and metastasis in gastric cancer cells.
Experimental cell research
Qiu R,Zhao S,Lu C,Xu Z,Shu E,Weng Q,Chen W,Fang S,Chen W,Zheng L,Zhao Z,Yang Y,Ji J
Sat Apr 01 00:00:00 UTC 2023
Zinc-finger protein CXXC5 promotes breast carcinogenesis by regulating the TSC1/mTOR signaling pathway.
The Journal of biological chemistry
Wang W,Zhang Z,Zhao M,Wang Y,Ge Y,Shan L
Sun Jan 01 00:00:00 UTC 2023
Zinc-finger protein CXXC5 promotes breast carcinogenesis by regulating the TSC1/mTOR signaling pathway.
The Journal of biological chemistry
Wang W,Zhang Z,Zhao M,Wang Y,Ge Y,Shan L
Sun Jan 01 00:00:00 UTC 2023
Cullin neddylation inhibitor attenuates hyperglycemia by enhancing hepatic insulin signaling through insulin receptor substrate stabilization.
Proceedings of the National Academy of Sciences of the United States of America
Chen C,Gu L,Matye DJ,Clayton YD,Hasan MN,Wang Y,Friedman JE,Li T
Tue Feb 08 00:00:00 UTC 2022
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
Cell
Mo X,Niu Q,Ivanov AA,Tsang YH,Tang C,Shu C,Li Q,Qian K,Wahafu A,Doyle SP,Cicka D,Yang X,Fan D,Reyna MA,Cooper LAD,Moreno CS,Zhou W,Owonikoko TK,Lonial S,Khuri FR,Du Y,Ramalingam SS,Mills GB,Fu H
Thu May 26 00:00:00 UTC 2022
Comparative maternal protein profiling of mouse biparental and uniparental embryos.
GigaScience
Chen F,Ma B,Lin Y,Luo X,Xu T,Zhang Y,Chen F,Li Y,Zhang Y,Luo B,Zhang Q,Xie X
Sat Sep 03 00:00:00 UTC 2022
In Situ Peroxidase Labeling Followed by Mass-Spectrometry Reveals TIA1 Interactome.
Biology
Gourdomichali O,Zonke K,Kattan FG,Makridakis M,Kontostathi G,Vlahou A,Doxakis E
Fri Feb 11 00:00:00 UTC 2022
Aurora kinase a promotes the progression of papillary thyroid carcinoma by activating the mTORC2-AKT signalling pathway.
Cell & bioscience
Zhao Z,Wang H,Kang N,Wang Z,Hou X,Hu L,Qie S,Guo J,Wei S,Ruan X,Zheng X
Mon Dec 05 00:00:00 UTC 2022
Aurora kinase a promotes the progression of papillary thyroid carcinoma by activating the mTORC2-AKT signalling pathway.
Cell & bioscience
Zhao Z,Wang H,Kang N,Wang Z,Hou X,Hu L,Qie S,Guo J,Wei S,Ruan X,Zheng X
Mon Dec 05 00:00:00 UTC 2022
A small molecule inhibitor of the UBE2F-CRL5 axis induces apoptosis and radiosensitization in lung cancer.
Signal transduction and targeted therapy
Xu T,Ma Q,Li Y,Yu Q,Pan P,Zheng Y,Li Z,Xiong X,Hou T,Yu B,Liu H,Sun Y
Mon Oct 17 00:00:00 UTC 2022
Evaluation of HZX-960, a novel DCN1-UBC12 interaction inhibitor, as a potential antifibrotic compound for liver fibrosis.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Zhou W,Dong G,Gao G,He Z,Xu J,Aziz S,Ma L,Zhao W
Mon Aug 01 00:00:00 UTC 2022
Neddylation inhibition induces glutamine uptake and metabolism by targeting CRL3SPOP E3 ligase in cancer cells.
Nature communications
Zhou Q,Lin W,Wang C,Sun F,Ju S,Chen Q,Wang Y,Chen Y,Li H,Wang L,Hu Z,Jin H,Wang X,Sun Y
Tue May 31 00:00:00 UTC 2022
SMYD3 associates with the NuRD (MTA1/2) complex to regulate transcription and promote proliferation and invasiveness in hepatocellular carcinoma cells.
BMC biology
Yang Y,Qiu R,Zhao S,Shen L,Tang B,Weng Q,Xu Z,Zheng L,Chen W,Shu G,Wang Y,Zhao Z,Chen M,Ji J
Tue Dec 27 00:00:00 UTC 2022
Early growth response-1 is a new substrate of the GSK3β-FBXW7 axis.
Neoplasia (New York, N.Y.)
Yin L,Zhang J,Sun Y
Thu Dec 01 00:00:00 UTC 2022
Discovery of Potent and Selective 2-(Benzylthio)pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects.
Journal of medicinal chemistry
He ZX,An Q,Wei B,Zhou WJ,Wei BF,Gong YP,Zhang X,Gao G,Dong GJ,Huo JL,Zhang XH,Yang FF,Liu HM,Ma LY,Zhao W
Thu Jan 13 00:00:00 UTC 2022
CUL4B increases platinum-based drug resistance in colorectal cancer through EMT: A study in its mechanism.
Journal of cellular and molecular medicine
Luo JW,Wang CM,Su JW,Yi TZ,Tang SH
Thu Dec 01 00:00:00 UTC 2022
MOF negatively regulates estrogen receptor α signaling via CUL4B-mediated protein degradation in breast cancer.
Frontiers in oncology
Zhang X,Yang Y,Li D,Wu Z,Liu H,Zhao Z,Zhu H,Xie F,Li X
Tue Oct 11 00:00:00 UTC 2022
AMPK induces degradation of the transcriptional repressor PROX1 impairing branched amino acid metabolism and tumourigenesis.
Nature communications
Wang Y,Luo M,Wang F,Tong Y,Li L,Shu Y,Qiao K,Zhang L,Yan G,Liu J,Ji H,Xie Y,Zhang Y,Gao WQ,Liu Y
Thu Nov 24 00:00:00 UTC 2022
AMPK induces degradation of the transcriptional repressor PROX1 impairing branched amino acid metabolism and tumourigenesis.
Nature communications
Wang Y,Luo M,Wang F,Tong Y,Li L,Shu Y,Qiao K,Zhang L,Yan G,Liu J,Ji H,Xie Y,Zhang Y,Gao WQ,Liu Y
Thu Nov 24 00:00:00 UTC 2022
FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells.
Cell
Shen JZ,Qiu Z,Wu Q,Finlay D,Garcia G,Sun D,Rantala J,Barshop W,Hope JL,Gimple RC,Sangfelt O,Bradley LM,Wohlschlegel J,Rich JN,Spruck C
Thu Jan 21 00:00:00 UTC 2021
FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells.
Cell
Shen JZ,Qiu Z,Wu Q,Finlay D,Garcia G,Sun D,Rantala J,Barshop W,Hope JL,Gimple RC,Sangfelt O,Bradley LM,Wohlschlegel J,Rich JN,Spruck C
Thu Jan 21 00:00:00 UTC 2021
The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma.
Molecular cell
Heider M,Eichner R,Stroh J,Morath V,Kuisl A,Zecha J,Lawatscheck J,Baek K,Garz AK,Rudelius M,Deuschle FC,Keller U,Lemeer S,Verbeek M,Götze KS,Skerra A,Weber WA,Buchner J,Schulman BA,Kuster B,Fernández-Sáiz V,Bassermann F
Thu Mar 18 00:00:00 UTC 2021
A functional motif of long noncoding RNA Nron against osteoporosis.
Nature communications
Jin F,Li J,Zhang YB,Liu X,Cai M,Liu M,Li M,Ma C,Yue R,Zhu Y,Lai R,Wang Z,Ji X,Wei H,Dong J,Liu Z,Wang Y,Sun Y,Wang X
Thu Jun 03 00:00:00 UTC 2021
A functional motif of long noncoding RNA Nron against osteoporosis.
Nature communications
Jin F,Li J,Zhang YB,Liu X,Cai M,Liu M,Li M,Ma C,Yue R,Zhu Y,Lai R,Wang Z,Ji X,Wei H,Dong J,Liu Z,Wang Y,Sun Y,Wang X
Thu Jun 03 00:00:00 UTC 2021
The Mediator subunit MED20 organizes the early adipogenic complex to promote development of adipose tissues and diet-induced obesity.
Cell reports
Tang WS,Weng L,Wang X,Liu CQ,Hu GS,Yin ST,Tao Y,Hong NN,Guo H,Liu W,Wang HR,Zhao TJ
Tue Jul 06 00:00:00 UTC 2021
Cardioprotective effect of MLN4924 on ameliorating autophagic flux impairment in myocardial ischemia-reperfusion injury by Sirt1.
Redox biology
Zhang J,Cui J,Zhao F,Yang L,Xu X,Shi Y,Wei B
Fri Oct 01 00:00:00 UTC 2021
DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity.
Cell reports
Wang X,Wang HY,Hu GS,Tang WS,Weng L,Zhang Y,Guo H,Yao SS,Liu SY,Zhang GL,Han Y,Liu M,Zhang XD,Cen X,Shen HF,Xiao N,Liu CQ,Wang HR,Huang J,Liu W,Li P,Zhao TJ
Tue Jun 22 00:00:00 UTC 2021
Overexpressed NEDD8 as a potential therapeutic target in esophageal squamous cell carcinoma.
Cancer biology & medicine
Xian J,Wang S,Jiang Y,Li L,Cai L,Chen P,Liu Y,Zeng X,Chen G,Ding C,Hoffman RM,Jia L,Zhao H,Zhang Y
Thu Mar 18 00:00:00 UTC 2021
Development of phenyltriazole thiol-based derivatives as highly potent inhibitors of DCN1-UBC12 interaction.
European journal of medicinal chemistry
Zhou W,Xu C,Dong G,Qiao H,Yang J,Liu H,Ding L,Sun K,Zhao W
Wed May 05 00:00:00 UTC 2021
Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the receptor protein of CRL2Prame complex.
Cell death and differentiation
Zhang W,Li L,Cai L,Liang Y,Xu J,Liu Y,Zhou L,Ding C,Zhang Y,Zhao H,Qin J,Shao Z,Wei W,Jia L
Tue Jun 01 00:00:00 UTC 2021
Tumor suppressor DCAF15 inhibits epithelial-mesenchymal transition by targeting ZEB1 for proteasomal degradation in hepatocellular carcinoma.
Aging
Dong X,Han Y,Zhang E,Wang Y,Zhang P,Wang C,Zhong L,Li Q
Sun Apr 04 00:00:00 UTC 2021
CUL4high Lung Adenocarcinomas Are Dependent on the CUL4-p21 Ubiquitin Signaling for Proliferation and Survival.
The American journal of pathology
Wang Y,Yan F,Nasar A,Chen ZS,Altorki NK,Stiles B,Narula N,Zhou P
Wed Sep 01 00:00:00 UTC 2021
CUL4high Lung Adenocarcinomas Are Dependent on the CUL4-p21 Ubiquitin Signaling for Proliferation and Survival.
The American journal of pathology
Wang Y,Yan F,Nasar A,Chen ZS,Altorki NK,Stiles B,Narula N,Zhou P
Wed Sep 01 00:00:00 UTC 2021
The E3 ubiquitin ligase Cul4b promotes CD4+ T cell expansion by aiding the repair of damaged DNA.
PLoS biology
Dar AA,Sawada K,Dybas JM,Moser EK,Lewis EL,Park E,Fazelinia H,Spruce LA,Ding H,Seeholzer SH,Oliver PM
Mon Feb 01 00:00:00 UTC 2021
The CRL4VPRBP(DCAF1) E3 ubiquitin ligase directs constitutive RAG1 degradation in a non-lymphoid cell line.
PloS one
Schabla NM,Swanson PC
Thu Nov 25 00:00:00 UTC 2021
Roles of the ubiquitin ligase CUL4B and ADP-ribosyltransferase TiPARP in TCDD-induced nuclear export and proteasomal degradation of the transcription factor AHR.
The Journal of biological chemistry
Rijo MP,Diani-Moore S,Yang C,Zhou P,Rifkind AB
Sun Aug 01 00:00:00 UTC 2021
The PRDM14-CtBP1/2-PRC2 complex regulates transcriptional repression during the transition from primed to naïve pluripotency.
Journal of cell science
Yamamoto M,Suwa Y,Sugiyama K,Okashita N,Kawaguchi M,Tani N,Matsubara K,Nakamura A,Seki Y
Fri Aug 14 00:00:00 UTC 2020
Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Bayraktar G,Yuanxiang P,Confettura AD,Gomes GM,Raza SA,Stork O,Tajima S,Suetake I,Karpova A,Yildirim F,Kreutz MR
Sun Nov 01 00:00:00 UTC 2020
Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Bayraktar G,Yuanxiang P,Confettura AD,Gomes GM,Raza SA,Stork O,Tajima S,Suetake I,Karpova A,Yildirim F,Kreutz MR
Sun Nov 01 00:00:00 UTC 2020
Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Bayraktar G,Yuanxiang P,Confettura AD,Gomes GM,Raza SA,Stork O,Tajima S,Suetake I,Karpova A,Yildirim F,Kreutz MR
Sun Nov 01 00:00:00 UTC 2020
Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Bayraktar G,Yuanxiang P,Confettura AD,Gomes GM,Raza SA,Stork O,Tajima S,Suetake I,Karpova A,Yildirim F,Kreutz MR
Sun Nov 01 00:00:00 UTC 2020
CUL4-DDB1-CRBN E3 Ubiquitin Ligase Regulates Proteostasis of ClC-2 Chloride Channels: Implication for Aldosteronism and Leukodystrophy.
Cells
Fu SJ,Hu MC,Peng YJ,Fang HY,Hsiao CT,Chen TY,Jeng CJ,Tang CY
Tue May 26 00:00:00 UTC 2020
The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth.
Cell death and differentiation
Cui D,Dai X,Shu J,Ma Y,Wei D,Xiong X,Zhao Y
Sun Mar 01 00:00:00 UTC 2020
Induction of NEDD8-conjugating enzyme E2 UBE2F by platinum protects lung cancer cells from apoptosis and confers to platinum-insensitivity.
Cell death & disease
Zhou L,Zhu J,Chen W,Jiang Y,Hu T,Wang Y,Ye X,Zhan M,Ji C,Xu Z,Wang X,Gu Y,Jia L
Thu Nov 12 00:00:00 UTC 2020
CUL4 E3 ligase regulates the proliferation and apoptosis of lung squamous cell carcinoma and small cell lung carcinoma.
Cancer biology & medicine
Li T,Wu S,Jia L,Cao W,Yao Y,Zhao G,Li H
Fri May 15 00:00:00 UTC 2020
Effective targeting of the ubiquitin-like modifier NEDD8 for lung adenocarcinoma treatment.
Cell biology and toxicology
Jiang Y,Cheng W,Li L,Zhou L,Liang Y,Zhang W,Chen W,Wang S,Zhao H,Chen G,Zhou W,Ji G,Zhang Y,Hoffman RM,Wang M,Jia L
Sat Aug 01 00:00:00 UTC 2020
The CRL3BTBD9 E3 ubiquitin ligase complex targets TNFAIP1 for degradation to suppress cancer cell migration.
Signal transduction and targeted therapy
Li L,Zhang W,Liu Y,Liu X,Cai L,Kang J,Zhang Y,Chen W,Dong C,Zhang Y,Wang M,Wei W,Jia L
Fri Apr 24 00:00:00 UTC 2020
Rational discovery of molecular glue degraders via scalable chemical profiling.
Nature chemical biology
Mayor-Ruiz C,Bauer S,Brand M,Kozicka Z,Siklos M,Imrichova H,Kaltheuner IH,Hahn E,Seiler K,Koren A,Petzold G,Fellner M,Bock C,Müller AC,Zuber J,Geyer M,Thomä NH,Kubicek S,Winter GE
Sun Nov 01 00:00:00 UTC 2020
Gossypol inhibits cullin neddylation by targeting SAG-CUL5 and RBX1-CUL1 complexes.
Neoplasia (New York, N.Y.)
Yu Q,Hu Z,Shen Y,Jiang Y,Pan P,Hou T,Pan ZQ,Huang J,Sun Y
Wed Apr 01 00:00:00 UTC 2020
Regulation of liver receptor homologue-1 by DDB2 E3 ligase activity is critical for hepatic glucose metabolism.
Scientific reports
Lai TC,Hu MC
Thu Mar 28 00:00:00 UTC 2019
Cul4-Ddb1 ubiquitin ligases facilitate DNA replication-coupled sister chromatid cohesion through regulation of cohesin acetyltransferase Esco2.
PLoS genetics
Sun H,Zhang J,Xin S,Jiang M,Zhang J,Li Z,Cao Q,Lou H
Fri Feb 01 00:00:00 UTC 2019
Development of Highly Potent, Selective, and Cellular Active Triazolo[1,5- a]pyrimidine-Based Inhibitors Targeting the DCN1-UBC12 Protein-Protein Interaction.
Journal of medicinal chemistry
Wang S,Zhao L,Shi XJ,Ding L,Yang L,Wang ZZ,Shen D,Tang K,Li XJ,Mamun M,Li H,Yu B,Zheng YC,Wang S,Liu HM
Thu Mar 14 00:00:00 UTC 2019
Potent 5-Cyano-6-phenyl-pyrimidin-Based Derivatives Targeting DCN1-UBE2M Interaction.
Journal of medicinal chemistry
Zhou W,Ma L,Ding L,Guo Q,He Z,Yang J,Qiao H,Li L,Yang J,Yu S,Zhao L,Wang S,Liu HM,Suo Z,Zhao W
Thu Jun 13 00:00:00 UTC 2019
CUL4B promotes prostate cancer progression by forming positive feedback loop with SOX4.
Oncogenesis
Qi M,Hu J,Cui Y,Jiao M,Feng T,Li X,Pang Y,Chen X,Qin R,Su P,Zhang H,Wang Y,Gong Y,Han B
Thu Mar 14 00:00:00 UTC 2019
The orphan nuclear receptor SHP regulates ER stress response by inhibiting XBP1s degradation.
Genes & development
Sun S,Kelekar S,Kliewer SA,Mangelsdorf DJ
Thu Aug 01 00:00:00 UTC 2019
UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F.
Molecular cell
Zhou W,Xu J,Tan M,Li H,Li H,Wei W,Sun Y
Thu Jun 21 00:00:00 UTC 2018
UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F.
Molecular cell
Zhou W,Xu J,Tan M,Li H,Li H,Wei W,Sun Y
Thu Jun 21 00:00:00 UTC 2018
Cullin-3-KCTD10-mediated CEP97 degradation promotes primary cilium formation.
Journal of cell science
Nagai T,Mukoyama S,Kagiwada H,Goshima N,Mizuno K
Wed Dec 12 00:00:00 UTC 2018
Cullin-3-KCTD10-mediated CEP97 degradation promotes primary cilium formation.
Journal of cell science
Nagai T,Mukoyama S,Kagiwada H,Goshima N,Mizuno K
Wed Dec 12 00:00:00 UTC 2018
High-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein-Protein Interaction.
Journal of medicinal chemistry
Zhou H,Zhou W,Zhou B,Liu L,Chern TR,Chinnaswamy K,Lu J,Bernard D,Yang CY,Li S,Wang M,Stuckey J,Sun Y,Wang S
Thu Mar 08 00:00:00 UTC 2018
Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.
Science (New York, N.Y.)
Han T,Goralski M,Gaskill N,Capota E,Kim J,Ting TC,Xie Y,Williams NS,Nijhawan D
Fri Apr 28 00:00:00 UTC 2017
Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.
Science (New York, N.Y.)
Han T,Goralski M,Gaskill N,Capota E,Kim J,Ting TC,Xie Y,Williams NS,Nijhawan D
Fri Apr 28 00:00:00 UTC 2017
Sirtuin 7-dependent deacetylation of DDB1 regulates the expression of nuclear receptor TR4.
Biochemical and biophysical research communications
Karim MF,Yoshizawa T,Sobuz SU,Sato Y,Yamagata K
Sat Aug 19 00:00:00 UTC 2017
Sirtuin 7-dependent deacetylation of DDB1 regulates the expression of nuclear receptor TR4.
Biochemical and biophysical research communications
Karim MF,Yoshizawa T,Sobuz SU,Sato Y,Yamagata K
Sat Aug 19 00:00:00 UTC 2017
Dysregulation of CUL4A and CUL4B Ubiquitin Ligases in Lung Cancer.
The Journal of biological chemistry
Jia L,Yan F,Cao W,Chen Z,Zheng H,Li H,Pan Y,Narula N,Ren X,Li H,Zhou P
Fri Feb 17 00:00:00 UTC 2017
Dysregulation of CUL4A and CUL4B Ubiquitin Ligases in Lung Cancer.
The Journal of biological chemistry
Jia L,Yan F,Cao W,Chen Z,Zheng H,Li H,Pan Y,Narula N,Ren X,Li H,Zhou P
Fri Feb 17 00:00:00 UTC 2017
Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity.
Nature medicine
Eichner R,Heider M,Fernández-Sáiz V,van Bebber F,Garz AK,Lemeer S,Rudelius M,Targosz BS,Jacobs L,Knorn AM,Slawska J,Platzbecker U,Germing U,Langer C,Knop S,Einsele H,Peschel C,Haass C,Keller U,Schmid B,Götze KS,Kuster B,Bassermann F
Fri Jul 01 00:00:00 UTC 2016
A transcriptional target of androgen receptor, miR-421 regulates proliferation and metabolism of prostate cancer cells.
The international journal of biochemistry & cell biology
Meng D,Yang S,Wan X,Zhang Y,Huang W,Zhao P,Li T,Wang L,Huang Y,Li T,Li Y
Fri Apr 01 00:00:00 UTC 2016
A transcriptional target of androgen receptor, miR-421 regulates proliferation and metabolism of prostate cancer cells.
The international journal of biochemistry & cell biology
Meng D,Yang S,Wan X,Zhang Y,Huang W,Zhao P,Li T,Wang L,Huang Y,Li T,Li Y
Fri Apr 01 00:00:00 UTC 2016
Cell Autonomous and Nonautonomous Function of CUL4B in Mouse Spermatogenesis.
The Journal of biological chemistry
Yin Y,Liu L,Yang C,Lin C,Veith GM,Wang C,Sutovsky P,Zhou P,Ma L
Fri Mar 25 00:00:00 UTC 2016
Cell Autonomous and Nonautonomous Function of CUL4B in Mouse Spermatogenesis.
The Journal of biological chemistry
Yin Y,Liu L,Yang C,Lin C,Veith GM,Wang C,Sutovsky P,Zhou P,Ma L
Fri Mar 25 00:00:00 UTC 2016
Regulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90β.
Scientific reports
Peng YJ,Huang JJ,Wu HH,Hsieh HY,Wu CY,Chen SC,Chen TY,Tang CY
Thu Sep 01 00:00:00 UTC 2016
Regulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90β.
Scientific reports
Peng YJ,Huang JJ,Wu HH,Hsieh HY,Wu CY,Chen SC,Chen TY,Tang CY
Thu Sep 01 00:00:00 UTC 2016
Tumor suppressor protein Lgl mediates G1 cell cycle arrest at high cell density by forming an Lgl-VprBP-DDB1 complex.
Molecular biology of the cell
Yamashita K,Ide M,Furukawa KT,Suzuki A,Hirano H,Ohno S
Wed Jul 01 00:00:00 UTC 2015
Tumor suppressor protein Lgl mediates G1 cell cycle arrest at high cell density by forming an Lgl-VprBP-DDB1 complex.
Molecular biology of the cell
Yamashita K,Ide M,Furukawa KT,Suzuki A,Hirano H,Ohno S
Wed Jul 01 00:00:00 UTC 2015
The Cullin 4A/B-DDB1-Cereblon E3 Ubiquitin Ligase Complex Mediates the Degradation of CLC-1 Chloride Channels.
Scientific reports
Chen YA,Peng YJ,Hu MC,Huang JJ,Chien YC,Wu JT,Chen TY,Tang CY
Fri May 29 00:00:00 UTC 2015
The neddylation-cullin 2-RBX1 E3 ligase axis targets tumor suppressor RhoB for degradation in liver cancer.
Molecular & cellular proteomics : MCP
Xu J,Li L,Yu G,Ying W,Gao Q,Zhang W,Li X,Ding C,Jiang Y,Wei D,Duan S,Lei Q,Li P,Shi T,Qian X,Qin J,Jia L
Sun Mar 01 00:00:00 UTC 2015
SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway.
Cell metabolism
Yoshizawa T,Karim MF,Sato Y,Senokuchi T,Miyata K,Fukuda T,Go C,Tasaki M,Uchimura K,Kadomatsu T,Tian Z,Smolka C,Sawa T,Takeya M,Tomizawa K,Ando Y,Araki E,Akaike T,Braun T,Oike Y,Bober E,Yamagata K
Tue Apr 01 00:00:00 UTC 2014
SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway.
Cell metabolism
Yoshizawa T,Karim MF,Sato Y,Senokuchi T,Miyata K,Fukuda T,Go C,Tasaki M,Uchimura K,Kadomatsu T,Tian Z,Smolka C,Sawa T,Takeya M,Tomizawa K,Ando Y,Araki E,Akaike T,Braun T,Oike Y,Bober E,Yamagata K
Tue Apr 01 00:00:00 UTC 2014
AMBRA1 interplay with cullin E3 ubiquitin ligases regulates autophagy dynamics.
Developmental cell
Antonioli M,Albiero F,Nazio F,Vescovo T,Perdomo AB,Corazzari M,Marsella C,Piselli P,Gretzmeier C,Dengjel J,Cecconi F,Piacentini M,Fimia GM
Mon Dec 22 00:00:00 UTC 2014
AMBRA1 interplay with cullin E3 ubiquitin ligases regulates autophagy dynamics.
Developmental cell
Antonioli M,Albiero F,Nazio F,Vescovo T,Perdomo AB,Corazzari M,Marsella C,Piselli P,Gretzmeier C,Dengjel J,Cecconi F,Piacentini M,Fimia GM
Mon Dec 22 00:00:00 UTC 2014
CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.
Science (New York, N.Y.)
Yu C,Zhang YL,Pan WW,Li XM,Wang ZW,Ge ZJ,Zhou JJ,Cang Y,Tong C,Sun QY,Fan HY
Fri Dec 20 00:00:00 UTC 2013
CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.
Science (New York, N.Y.)
Yu C,Zhang YL,Pan WW,Li XM,Wang ZW,Ge ZJ,Zhou JJ,Cang Y,Tong C,Sun QY,Fan HY
Fri Dec 20 00:00:00 UTC 2013
CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.
Science (New York, N.Y.)
Yu C,Zhang YL,Pan WW,Li XM,Wang ZW,Ge ZJ,Zhou JJ,Cang Y,Tong C,Sun QY,Fan HY
Fri Dec 20 00:00:00 UTC 2013
A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase.
The Journal of biological chemistry
Zhang S,Zhao H,Darzynkiewicz Z,Zhou P,Zhang Z,Lee EY,Lee MY
Fri Oct 11 00:00:00 UTC 2013
A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase.
The Journal of biological chemistry
Zhang S,Zhao H,Darzynkiewicz Z,Zhou P,Zhang Z,Lee EY,Lee MY
Fri Oct 11 00:00:00 UTC 2013
Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis.
Cell research
Liu L,Yin Y,Li Y,Prevedel L,Lacy EH,Ma L,Zhou P
Wed Aug 01 00:00:00 UTC 2012
Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis.
Cell research
Liu L,Yin Y,Li Y,Prevedel L,Lacy EH,Ma L,Zhou P
Wed Aug 01 00:00:00 UTC 2012
Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis.
Cell research
Liu L,Yin Y,Li Y,Prevedel L,Lacy EH,Ma L,Zhou P
Wed Aug 01 00:00:00 UTC 2012
Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis.
Cell research
Liu L,Yin Y,Li Y,Prevedel L,Lacy EH,Ma L,Zhou P
Wed Aug 01 00:00:00 UTC 2012
Cul4B regulates neural progenitor cell growth.
BMC neuroscience
Liu HC,Enikolopov G,Chen Y
Wed Sep 19 00:00:00 UTC 2012
Cul4B regulates neural progenitor cell growth.
BMC neuroscience
Liu HC,Enikolopov G,Chen Y
Wed Sep 19 00:00:00 UTC 2012
Cul4B regulates neural progenitor cell growth.
BMC neuroscience
Liu HC,Enikolopov G,Chen Y
Wed Sep 19 00:00:00 UTC 2012
Cul4B regulates neural progenitor cell growth.
BMC neuroscience
Liu HC,Enikolopov G,Chen Y
Wed Sep 19 00:00:00 UTC 2012
The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis.
Developmental biology
Yin Y,Lin C,Kim ST,Roig I,Chen H,Liu L,Veith GM,Jin RU,Keeney S,Jasin M,Moley K,Zhou P,Ma L
Mon Aug 01 00:00:00 UTC 2011
The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis.
Developmental biology
Yin Y,Lin C,Kim ST,Roig I,Chen H,Liu L,Veith GM,Jin RU,Keeney S,Jasin M,Moley K,Zhou P,Ma L
Mon Aug 01 00:00:00 UTC 2011
Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase.
Cancer cell
Aggarwal P,Vaites LP,Kim JK,Mellert H,Gurung B,Nakagawa H,Herlyn M,Hua X,Rustgi AK,McMahon SB,Diehl JA
Tue Oct 19 00:00:00 UTC 2010
Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase.
Cancer cell
Aggarwal P,Vaites LP,Kim JK,Mellert H,Gurung B,Nakagawa H,Herlyn M,Hua X,Rustgi AK,McMahon SB,Diehl JA
Tue Oct 19 00:00:00 UTC 2010
