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          • Primary Antibodies ›
          • CX3CL1 Antibodies

          Proteintech

          CX3CL1 Polyclonal Antibody

          View all (27) CX3CL1 antibodies

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          Cite CX3CL1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          CX3CL1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          CX3CL1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          CX3CL1 Antibody (32529-1-AP) in WB

          Various lysates were subjected to SDS PAGE followed by western blot with 32534-1-AP (Siglec-12 antibody) at dilution of 1:1,000 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CX3CL1 Antibody in Western Blot (WB)
          CX3CL1 Polyclonal Antibody

          Product Details

          32529-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          -

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          500 µg/mL

          Amount

          75 µg

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice

          Product Specific Information

          Sequence of this protein is as follows: TKCNITCHKM TSPIPVTLLI HYQLNQESCG KRAIILETRQ HRHFCADPKE KWVQDAMKHL DHQTAALTRN GGKFEKRVDN VTPRITSATR GLSPTALAKP ESATVEDLTL EPTAISQEAR RPMGTSQEPP AAVTGSSPST SKAQDAGLAA KPQSTGISEV AAVSTTIWPS SAVYQSGSSL WAEEKATESP PTIALSTQAS TTSSPKQNVG SEGQPPWVQE QDSTPEKSPG PEETNPVHTD IFQDRGPGST VHPSVAPTSS EKTPSPELVA SGSQAPKVEE PIHATADPQK LSVFITPVPD SQAATR

          Target Information

          Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: ABCD-3; C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; FK; Fractalkine; Neurotactin; small inducible cytokine subfamily D, 1; Small-inducible cytokine D1

          View more View less

          Gene Aliases: AB030188; ABCD-3; Acc1; AI848747; CX3C; Cx3cl1; Cxc3; D8Bwg0439e; Fkn; Scyd1

          View more View less

          UniProt ID: (Rat) O55145, (Mouse) O35188

          View more View less

          Entrez Gene ID: (Rat) 89808, (Mouse) 20312

          View more View less

          Function(s)
          chemokine activity cytokine activity cytokine intercellular signal molecule
          Process(es)
          response to hypoxia microglial cell activation positive regulation of neuroblast proliferation chemotaxis immune response cell adhesion aging positive regulation of macrophage chemotaxis cytokine-mediated signaling pathway platelet activation positive regulation of cell migration neutrophil chemotaxis positive regulation of transforming growth factor beta1 production wound healing positive regulation of angiogenesis positive regulation of cell adhesion negative regulation of vasoconstriction macrophage chemotaxis lymphocyte chemotaxis positive regulation of smooth muscle cell proliferation negative regulation of cytokine secretion positive regulation of inflammatory response positive regulation of calcium-independent cell-cell adhesion angiogenesis involved in wound healing inhibitory postsynaptic potential cell chemotaxis negative regulation of extrinsic apoptotic signaling pathway in absence of ligand leukocyte adhesive activation
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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