PA1-29220 detects CXCL1 from rat and mouse samples.
PA1-29220 has been successfully used in immunoprecipitation and Western blot applications. It is not suitable for use in immunohistochemistry applications.
The PA1-29220 immunogen is recombinant fragment - amino acids 1-72 of rat KC.
Store at 4°C for short term storage. For long term storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.
KC, a homolog of human and hamster gro/MGSA, is a 72 amino acid CXC chemokine originally cloned from rat macrophages and lung tissue. It is the mediator for recruitment and activation of neutrophils in rat lung inflammation models. Expression of KC can be upregulated by LPS and IL-1b stimulation. IFN-gamma blocks LPS induced expression of KC.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha-chemokine; C-X-C motif chemokine 1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); CINC-1; Cytokine-induced neutrophil chemoattractant 1; Fsp; gro; Gro1; GRO1 oncogene; Growth-regulated alpha protein; Hematopoietic synergistic factor; HSF; KC; KC(5-72); KC-T; KC/GR)-alpha; KC/GRO-alpha; Mgsa; N51; Platelet-derived growth factor-inducible protein KC; Scyb1; Secretory protein N51
Gene Aliases: CINC-1; Cinc1; Cxcl1; Fsp; Gro; Gro1; KC; Mgsa; N51; Scyb1