This Antibody was verified by Neutralization to ensure that the antibody binds to the antigen stated. View Details
In direct ELISAs and Western blots, less than 10% cross-reactivity with recombinant mouse CRG-2, recombinant human (rh) MIG, and rhGRO gamma.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.20 EU per 1 µg of the antibody by the LAL method.
IP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on neutrophils. Its functions include stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis. Mig and IP-10 share the same receptor, CXCR3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 10 kDa interferon gamma-induced protein; C-X-C motif chemokine 10; chemokine (C-X-C motif) ligand 10; CRG-2; CXCL10(1-73); gamma IP10; Gamma-IP10; gIP-10; Ifi10; INP10; Interferon Gamma Inducible Protein 10; interferon-inducible cytokine IP-10; mob-1; protein 10 from interferon (gamma)-induced cell line; Scyb10; small inducible cytokine subfamily B (Cys-X-Cys), member 10; Small-inducible cytokine B10
Gene Aliases: C7; crg-2; CXCL10; gIP-10; IFI10; INP10; IP-10; mob-1; SCYB10
UniProt ID: (Human) P02778
Entrez Gene ID: (Human) 3627