Invitrogen
This Antibody was verified by Neutralization to ensure that the antibody binds to the antigen stated.
Applications | Tested Dilution | Publications |
---|---|---|
Immunocytochemistry (ICC/IF) |
5-15 µg/mL | - |
Flow Cytometry (Flow) |
2.5 µg/1x10^6 cells | - |
Neutralization (Neu) |
1-4 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Goat / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
E. coli-derived recombinant human CXCL10/IP-10/CRG-2 |
Conjugate |
Unconjugated |
Form |
Lyophilized |
Concentration |
0.2 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS with 5% trehalose |
Contains |
No Preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2609777 |
In direct ELISAs and Western blots, less than 10% cross-reactivity with recombinant mouse CRG-2, recombinant human (rh) MIG, and rhGRO gamma.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.20 EU per 1 µg of the antibody by the LAL method.
IP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on neutrophils. Its functions include stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis. Mig and IP-10 share the same receptor, CXCR3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 10 kDa interferon gamma-induced protein; C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 10; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 10; CXC; CXC motif chemokine; CXCL; CXCL10(1-73); gamma IP10; Gamma-IP10; H-IP-10; interferon-inducible cytokine IP-10; M-IP-10; protein 10 from interferon (gamma)-induced cell line; small inducible cytokine subfamily B (Cys-X-Cys), member 10; Small-inducible cytokine B10
Gene Aliases: C7; crg-2; CXCL10; gIP-10; IFI10; INP10; IP-10; mob-1; SCYB10
UniProt ID: (Human) P02778
Entrez Gene ID: (Human) 3627
Molecular Function:
chemokine
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