Proteintech

CXCL2 Polyclonal Antibody

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CXCL2 Antibody (26791-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with 26791-1-AP (CXCL2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Product Details

26791-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 5 publications 5 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

ELISA (ELISA)

Assay-dependent

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CXCL2 fusion protein Ag25376

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: APLATELRCQ CLQTLQGIHL KNIQSVKVKS PGPHCAQTEV IATLKNGQKA CLNPASPMVK KIIEKMLKNG KSN

Target Information

Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Crosstalk among proximal tubular cells, macrophages, and fibroblasts in acute kidney injury: single-cell profiling from the perspective of ferroptosis.

Human cell

Wang Y,Shen Z,Mo S,Zhang H,Chen J,Zhu C,Lv S,Zhang D,Huang X,Gu Y,Yu X,Ding X,Zhang X

Mon Jul 01 00:00:00 UTC 2024

Crosstalk among proximal tubular cells, macrophages, and fibroblasts in acute kidney injury: single-cell profiling from the perspective of ferroptosis.

Human cell

Wang Y,Shen Z,Mo S,Zhang H,Chen J,Zhu C,Lv S,Zhang D,Huang X,Gu Y,Yu X,Ding X,Zhang X

Mon Jul 01 00:00:00 UTC 2024

Crosstalk among proximal tubular cells, macrophages, and fibroblasts in acute kidney injury: single-cell profiling from the perspective of ferroptosis.

Human cell

Wang Y,Shen Z,Mo S,Zhang H,Chen J,Zhu C,Lv S,Zhang D,Huang X,Gu Y,Yu X,Ding X,Zhang X

Mon Jul 01 00:00:00 UTC 2024

A novel resveratrol analog upregulates sirtuin 1 and inhibits inflammatory cell infiltration in acute pancreatitis.

Acta pharmacologica Sinica

Ren ZN,Yang J,Zhang MY,Huang YW,Song DX,Sun X,Pan LL,Sun J

Sun May 01 00:00:00 UTC 2022

A novel resveratrol analog upregulates sirtuin 1 and inhibits inflammatory cell infiltration in acute pancreatitis.

Acta pharmacologica Sinica

Ren ZN,Yang J,Zhang MY,Huang YW,Song DX,Sun X,Pan LL,Sun J

Sun May 01 00:00:00 UTC 2022

A novel resveratrol analog upregulates sirtuin 1 and inhibits inflammatory cell infiltration in acute pancreatitis.

Acta pharmacologica Sinica

Ren ZN,Yang J,Zhang MY,Huang YW,Song DX,Sun X,Pan LL,Sun J

Sun May 01 00:00:00 UTC 2022

MyD88 in Macrophages Enhances Liver Fibrosis by Activation of NLRP3 Inflammasome in HSCs.

International journal of molecular sciences

Ge S,Yang W,Chen H,Yuan Q,Liu S,Zhao Y,Zhang J

Wed Nov 17 00:00:00 UTC 2021

MyD88 in Macrophages Enhances Liver Fibrosis by Activation of NLRP3 Inflammasome in HSCs.

International journal of molecular sciences

Ge S,Yang W,Chen H,Yuan Q,Liu S,Zhao Y,Zhang J

Wed Nov 17 00:00:00 UTC 2021

MyD88 in Macrophages Enhances Liver Fibrosis by Activation of NLRP3 Inflammasome in HSCs.

International journal of molecular sciences

Ge S,Yang W,Chen H,Yuan Q,Liu S,Zhao Y,Zhang J

Wed Nov 17 00:00:00 UTC 2021

Macrophagic Extracellular Vesicle CXCL2 Recruits and Activates the Neutrophil CXCR2/PKC/NOX4 Axis in Sepsis.

Journal of immunology (Baltimore, Md. : 1950)

Wang G,Huang W,Wang S,Wang J,Cui W,Zhang W,Lou A,Geng S,Li X

Fri Oct 15 00:00:00 UTC 2021

Macrophagic Extracellular Vesicle CXCL2 Recruits and Activates the Neutrophil CXCR2/PKC/NOX4 Axis in Sepsis.

Journal of immunology (Baltimore, Md. : 1950)

Wang G,Huang W,Wang S,Wang J,Cui W,Zhang W,Lou A,Geng S,Li X

Fri Oct 15 00:00:00 UTC 2021

Macrophagic Extracellular Vesicle CXCL2 Recruits and Activates the Neutrophil CXCR2/PKC/NOX4 Axis in Sepsis.

Journal of immunology (Baltimore, Md. : 1950)

Wang G,Huang W,Wang S,Wang J,Cui W,Zhang W,Lou A,Geng S,Li X

Fri Oct 15 00:00:00 UTC 2021

Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.

International immunopharmacology

Wang L,Wang X,Kong L,Wang S,Huang K,Wu J,Wang C,Sun H,Liu K,Meng Q

Mon Nov 01 00:00:00 UTC 2021

Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.

International immunopharmacology

Wang L,Wang X,Kong L,Wang S,Huang K,Wu J,Wang C,Sun H,Liu K,Meng Q

Mon Nov 01 00:00:00 UTC 2021

Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.

International immunopharmacology

Wang L,Wang X,Kong L,Wang S,Huang K,Wu J,Wang C,Sun H,Liu K,Meng Q

Mon Nov 01 00:00:00 UTC 2021

Bioinformatics

Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 2; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 2; CINC-3; CXC; CXC motif chemokine; CXCL; Cytokine-induced neutrophil chemoattractant 3; GRO b; gro beta; GRO β; Gro-beta; GRO2 oncogene; GRObeta; Growth-regulated protein beta; GROβ; Macrophage inflammatory protein 2; Macrophage inflammatory protein 2-alpha; melanoma growth stimulatory activity beta; MGSA beta; MIP 2 a; MIP 2 alpha; MIP 2 α; MIP2; MIP2 a; MIP2 α; MIP2-alpha; small inducible cytokine subfamily, member 2

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Gene Aliases: CINC-2a; Cinc3; CXCL2; GRO2; GROB; MGSA-b; MIP-2; MIP-2a; MIP2; MIP2A; Scyb; SCYB2

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UniProt ID: (Human) P19875, (Mouse) P10889, (Rat) P30348

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Entrez Gene ID: (Human) 2920, (Mouse) 20310, (Rat) 114105

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Function(s)

protein binding chemokine activity CXCR chemokine receptor binding cytokine activity chemokine

Process(es)

response to molecule of bacterial origin chemotaxis inflammatory response immune response G-protein coupled receptor signaling pathway response to lipopolysaccharide regulation of cell proliferation cell chemotaxis chemokine-mediated signaling pathway positive regulation of neutrophil chemotaxis positive regulation of leukocyte chemotaxis positive regulation of cytosolic calcium ion concentration neutrophil chemotaxis leukocyte chemotaxis neuron death response to amphetamine response to heat response to gamma radiation response to estradiol wound healing response to glucocorticoid cellular response to lipopolysaccharide cellular response to interleukin-1

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CXCL2 Polyclonal Antibody

CXCL2 Antibody (26791-1-AP) in WB

Product Details

26791-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

ELISA (ELISA)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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