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Invitrogen
CXCL3 Polyclonal Antibody
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Product Details
PA5-103136
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CXCL3(Accession P19876), corresponding to amino acid residues E73-N107.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total GRO gamma.
Target Information
CXCL3 may play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 3; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 3; CINC-2; CXC; CXC motif chemokine; CXCL; cxcl3; Cytokine-induced neutrophil chemoattractant 2; cytokine-induced neutrophil chemoattractant-2; Dendritic cell inflammatory protein 1; gro gamma; GRO-gamma; GRO-gamma(1-73); GRO3 oncogene; Growth-regulated protein gamma; Macrophage inflammatory protein 2-alpha/beta; Macrophage inflammatory protein 2-beta; melanoma growth stimulatory activity gamma; MGSA gamma; MIP2-alpha/beta; MIP2-beta; unnamed protein product
Gene Aliases: Cinc-2; CINC-2b; Cinc2; CXCL3; Dcip1; Gm1960; GRO3; GROG; MIP-2b; MIP2B; SCYB3
UniProt ID: (Human) P19876, (Mouse) Q6W5C0, (Rat) Q10746
Entrez Gene ID: (Human) 2921, (Mouse) 330122, (Rat) 171551
chemotaxis
defense response
inflammatory response
immune response
signal transduction
neutrophil chemotaxis
killing of cells of other organism
antimicrobial humoral immune response mediated by antimicrobial peptide
positive regulation of leukocyte chemotaxis
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
response to lipopolysaccharide
regulation of cell proliferation
chemokine-mediated signaling pathway
hemopoiesis
cellular response to lipopolysaccharide
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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