In direct ELISAs, greater than 50% cross-reactivity with recombinant rat (rr) CINC-1, rrCINC-2 beta, and rrCINC-3 is observed, less than 25% cross-reactivity with recombinant mouse (rm) KC, rmMIP-2, recombinant human (rh) GRO alpha, rhGRO beta, and rhGRO gamma is observed, and less than 10% cross-reactivity with rhIL-8 is observed.
Reconstitute at 0.1 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
CXCL3 may play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.
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Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 3; CC motif chemokine; CCmotif chemokine; CINC-2; CXC; CXC motif chemokine; CXCL; Cytokine-induced neutrophil chemoattractant 2; cytokine-induced neutrophil chemoattractant-2; gro gamma; Macrophage inflammatory protein 2-alpha/beta; MIP2-alpha/beta
Gene Aliases: Cinc-2; Cinc2; Cxcl3; Gm1960
UniProt ID: (Rat) Q10746
Entrez Gene ID: (Rat) 171551