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The protein encoded by this gene is an inflammatory chemokine that belongs to the CXC chemokine family. This chemokine is produced concomitantly with interleukin-8 (IL8) in response to stimulation with either interleukin-1 (IL1) or tumor necrosis factor-alpha (TNFA). This chemokine is a potent chemotaxin involved in neutrophil activation.
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Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 5; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 5; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); CXC; CXC chemokine LIX; CXC motif chemokine; CXCL; Cytokine LIX; GCP-2(1-78); GCP-2(9-78); granulocyte chemotactic protein-2; small inducible cytokine B subfamily, member 5; small inducible cytokine subfamily B, member 15; Small-inducible cytokine B5
Gene Aliases: AMCF-II; Cxcl5; ENA-78; GCP-2; LIX; Scyb5; Scyb6
UniProt ID: (Mouse) P50228, (Rat) P97885
Entrez Gene ID: (Mouse) 20311, (Rat) 60665
Molecular Function:
chemokine
cytokine
signaling molecule
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